Pantsyrev Iu M, Fedorov E D, Timofeev M E, Mikhalev A I
Khirurgiia (Mosk). 2003(10):35-40.
Experience in diagnosis and treatment of 276 patients with Mallory--Weiss syndrome (MWS) is presented. Definition of the syndrome and brief historical review (from first description of disruption of esophageal-gastric connection to first report of successful hemostasis through endoscope) are given. Particular attention is devoted to etiology and pathogenesis of this syndrome. Clinical material and picture of disease, results of endoscopic diagnosis are analyzed, efficacy of endoscopic hemostasis and prophylaxis of hemorrhage is demonstrated. Indications to various methods of endoscopic hemostasis are regarded, results of treatment and lethal outcomes are analyzed. It is demonstrated that endoscopic procedures are the method of choice in the treatment of this disease reducing emergency surgery rate to 0.4%.
本文介绍了276例马洛里-魏斯综合征(MWS)患者的诊断和治疗经验。给出了该综合征的定义及简要的历史回顾(从首次描述食管-胃连接处破裂到首次报告通过内镜成功止血)。特别关注了该综合征的病因和发病机制。分析了临床资料、疾病表现、内镜诊断结果,展示了内镜止血和预防出血的疗效。考虑了各种内镜止血方法的适应证,分析了治疗结果和死亡情况。结果表明,内镜治疗是本病的首选治疗方法,可将急诊手术率降至0.4%。