使用负压封闭引流装置治疗复发性外阴佩吉特病。
Use of a vacuum-assisted closure device in the treatment of recurrent Paget's disease of the vulva.
作者信息
Shvartsman Hyun S, Langstein Howard, Worley Cynthia, Malpica Anais, Ramondetta Lois M
机构信息
Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030-4009, USA.
出版信息
Obstet Gynecol. 2003 Nov;102(5 Pt 2):1163-6. doi: 10.1016/s0029-7844(03)00716-6.
BACKGROUND
Paget's disease of the vulva is a rare malignancy for which common recurrence is related to inadequate surgical margins. Excision with adequate surgical margins might leave a large defect that does not readily heal.
CASE
A 41-year-old woman with recurrent Paget's disease of the vulva underwent a skinning excision of the vulva and perineum. A vacuum-assisted closure device was placed on the wound until final pathologic analysis confirmed the adequacy of surgical margins.
CONCLUSION
The vacuum-assisted closure device not only allowed us to safely temporize wound closure until the final histopathologic results, but also helped secure the skin graft to the large and irregular surface. Additional studies are needed to determine the effectiveness of vacuum-assisted closure device therapy in Paget's disease of the vulva.
背景
外阴佩吉特病是一种罕见的恶性肿瘤，常见的复发与手术切缘不充分有关。切除足够的手术切缘可能会留下一个不易愈合的大缺损。
病例
一名41岁复发性外阴佩吉特病女性接受了外阴和会阴的削除术。在伤口上放置了负压封闭引流装置，直至最终病理分析证实手术切缘足够。
结论
负压封闭引流装置不仅使我们能够安全地暂时闭合伤口直至最终组织病理学结果，还有助于将皮肤移植片固定在大的不规则表面上。需要进一步研究以确定负压封闭引流装置治疗外阴佩吉特病的有效性。
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