胃肠道炭疽：文献综述

Gastrointestinal anthrax: review of the literature.

作者信息

Beatty Mark E, Ashford David A, Griffin Patricia M, Tauxe Robert V, Sobel Jeremy

机构信息

Epidemic Intelligence Service, Division of Applied Public Health Training, Epidemiology Program Office, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

出版信息

Arch Intern Med. 2003 Nov 10;163(20):2527-31. doi: 10.1001/archinte.163.20.2527.

DOI:10.1001/archinte.163.20.2527

PMID:14609791

Abstract

Recent events have drawn attention to cases of inhalational and cutaneous anthrax associated with contaminated mail. Gastrointestinal anthrax, the disease caused by ingestion of Bacillus anthracis organisms, has rarely been reported in the United States. This review provides background information on the gastrointestinal form of the disease. We describe the clinical course of gastrointestinal anthrax, outline current therapy, review the microbiology of B anthracis, examine the epidemiology of natural outbreaks, discuss considerations regarding deliberate contamination, and summarize existing literature on the inactivation of spores present in food and water.

摘要

近期事件已引起人们对与受污染邮件相关的吸入性和皮肤炭疽病例的关注。胃肠道炭疽是由摄入炭疽杆菌生物体引起的疾病，在美国鲜有报道。本综述提供了关于该疾病胃肠道形式的背景信息。我们描述了胃肠道炭疽的临床病程，概述了当前的治疗方法，回顾了炭疽杆菌的微生物学，研究了自然爆发的流行病学，讨论了关于蓄意污染的相关考量，并总结了关于食品和水中存在的孢子灭活的现有文献。