Guller Ulrich, Jain Nitin, Hervey Sheleika, Purves Harriett, Pietrobon Ricardo
Department of Surgery, Duke University Medical Center, Durham, NC, USA.
Arch Surg. 2003 Nov;138(11):1179-86. doi: 10.1001/archsurg.138.11.1179.
Laparoscopic colectomy has significant advantages over open colectomy in the treatment of diverticular disease with respect to the length of hospital stay, routine hospital discharge, and postoperative morbidity and mortality.
Retrospective secondary data analysis.
Patients with primary International Classification of Diseases, Ninth Revision, Clinical Modification procedure codes for laparoscopic (709 patients [3.8%]) and open sigmoid resection (17 735 patients [96.2%]) were selected from the 1998, 1999, and 2000 Nationwide Inpatient Samples. These databases represent 20% stratified probability samples of all US community hospital discharges. Sampling weights were used to allow generalization of the study findings to the overall US population. Multiple linear and logistic regression analyses were performed to assess the risk-adjusted association between the surgery type and patient outcomes.
Length of hospital stay, in-hospital complications, in-hospital mortality, and the rate of routine discharge.
The patients had a mean age of 59.8 years; they were preponderantly white (89.1%) and female (54.0%). After adjusting for other covariates, laparoscopic sigmoidectomy was associated with a shorter mean hospital stay (laparoscopic sigmoidectomy vs open sigmoidectomy, 7.47 vs 9.37 days; P<.001), fewer gastrointestinal tract complications (odds ratio, 0.57; 95% confidence interval, 0.35-0.93; P =.03), a lower overall complication rate (odds ratio, 0.64; 95% confidence interval, 0.47-0.88; P =.007), and a higher routine hospital discharge rate (odds ratio, 2.21; 95% confidence interval, 1.51-3.21; P<.001).
Laparoscopic sigmoid resection in patients with diverticular disease has statistically and clinically significant advantages over open sigmoid resection with respect to the length of hospital stay, rate of routine hospital discharge, and postoperative in-hospital morbidity.
在治疗憩室病方面,腹腔镜结肠切除术相较于开放结肠切除术,在住院时间、常规出院情况以及术后发病率和死亡率方面具有显著优势。
回顾性二次数据分析。
从1998年、1999年和2000年的全国住院患者样本中选取主要国际疾病分类第九版临床修订版程序代码为腹腔镜手术(709例患者[3.8%])和开放性乙状结肠切除术(17735例患者[96.2%])的患者。这些数据库代表了美国所有社区医院出院患者的20%分层概率样本。使用抽样权重以便将研究结果推广至美国总体人群。进行了多项线性和逻辑回归分析,以评估手术类型与患者预后之间的风险调整关联。
住院时间、院内并发症、院内死亡率以及常规出院率。
患者的平均年龄为59.8岁;他们以白人为主(89.1%),女性居多(54.0%)。在对其他协变量进行调整后,腹腔镜乙状结肠切除术与较短的平均住院时间相关(腹腔镜乙状结肠切除术与开放性乙状结肠切除术相比,分别为7.47天和9.37天;P<0.001),胃肠道并发症更少(优势比,0.57;95%置信区间,0.35 - 0.93;P = 0.03),总体并发症发生率更低(优势比,0.64;95%置信区间,0.47 - 0.88;P = 0.007),以及更高的常规出院率(优势比,2.21;95%置信区间,1.51 - 3.21;P<0.001)。
对于憩室病患者,腹腔镜乙状结肠切除术在住院时间、常规出院率和术后院内发病率方面,相较于开放性乙状结肠切除术具有统计学和临床意义上的显著优势。