Labropoulos N, Oh D S, Golts E, Kang S S, Mansour M A, Baker W H
Department of Surgery, Loyola University Medical Center, Maywood, IL 60153-3304, USA.
Int Angiol. 2003 Sep;22(3):317-21.
The risk of deep vein thrombosis (DVT) in the peri-operative period is significant, but can be reduced with the use of mechanical intermittent pneumatic compression (IPC). These devices have reached widespread use in hospitals and have been found to be effective prophylactic measures against DVT. This study evaluates the latest design features of one particular IPC device in comparison to current models.
Duplex ultrasound scanning was performed on 40 lower extremities of 20 healthy volunteers before and during the application of the IPC device (VenaFlow System, Aircas, NJ, USA. Two hemodynamic parameters were measured, acceleration time from spontaneous baseline venous flow and peak vein velocity. All measurements were obtained by scanning proximal to the saphenofemoral junction in the common femoral vein in both extremities for each subject. Data were obtained from 3 compression cycles and averaged for each extremity. Results were compared with a recent prospective study form our center using a slow-filling and a rapid-filling sequential IPC devices.
The medians for spontaneous average peak velocities at rest of the right and left lower extremities were 26 cm/s and 24.1 cm/s. The median augmented peak velocities during the compression cycle of the device in the right and left side were 79.6 cm/s and 79.0 cm/s. This represented a 306.2% increase in average peak velocity on the right side and a 327.8% increase on the left side. The median acceleration time was 305 ms +/- 40 in the left and 310 ms +/- 50 in the right limb. There was no statistically significant difference in the spontaneous and augmented velocities between the right and left lower extremities in each subject. In comparison to existing slow- and rapid-filling IPC devices the VenaFlow System had superior peak velocities and shorter acceleration times.
The use of elliptical, sequential and rapid-filling compression of the leg with overlapping air-cells produces significant hemodynamic changes in the common femoral vein, which are superior to other sequential slow- or rapid-filling IPC devices. Randomized studies should be performed to determine the efficacy of this new device in DVT prevention.
围手术期深静脉血栓形成(DVT)的风险很大,但使用机械间歇性气动压迫(IPC)可降低该风险。这些装置已在医院广泛使用,并被发现是预防DVT的有效措施。本研究评估了一种特定IPC装置与当前型号相比的最新设计特点。
在应用IPC装置(VenaFlow系统,美国新泽西州Aircas公司)之前和期间,对20名健康志愿者的40条下肢进行了双功超声扫描。测量了两个血流动力学参数,即自基线静脉血流的加速时间和静脉峰值流速。所有测量均通过扫描每个受试者双下肢股总静脉隐股交界处近端获得。数据来自3个压迫周期,并对每个下肢进行平均。结果与我们中心最近一项使用缓慢充盈和快速充盈顺序IPC装置的前瞻性研究进行了比较。
右下肢和左下肢静息时自发平均峰值流速的中位数分别为26 cm/s和24.1 cm/s。装置压迫周期期间右侧和左侧的增强峰值流速中位数分别为79.6 cm/s和79.0 cm/s。这代表右侧平均峰值流速增加了306.2%,左侧增加了327.8%。左下肢和右下肢的加速时间中位数分别为305 ms±40和310 ms±50。每个受试者的右下肢和左下肢之间,自发和增强流速没有统计学上的显著差异。与现有的缓慢充盈和快速充盈IPC装置相比,VenaFlow系统具有更高的峰值流速和更短的加速时间。
使用带有重叠气囊的腿部椭圆形、顺序性和快速充盈压迫会在股总静脉中产生显著的血流动力学变化,这优于其他顺序性缓慢或快速充盈的IPC装置。应进行随机研究以确定这种新装置在预防DVT方面的疗效。