Smirnov V V, Bondarenko A S, Gladun N P
Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154 Zabolotny St., Kyiv, 03143, Ukraine.
Mikrobiol Z. 2003 Jul-Aug;65(4):17-22.
Complex drug cerbiden has been studied in vitro for the antifungal activity of its components. It has been established that the spectrum of antifungal effect and activity of cerbiden, with respect to fungi conditionally pathogenic for people, is determined by antibiotic compounds--aromatic carbohydrate phenylheptatryin and sesquiterpene phenol cernusol. They process a spectrum of antifungal activity analogous to cerbiden and activity close to Candida spp., some basidial yeast, dermatophytes, a number of Mucorales.
复方药物塞尔比登已在体外对其成分的抗真菌活性进行了研究。已确定,塞尔比登对人类条件致病性真菌的抗真菌作用谱和活性由抗生素化合物——芳香碳水化合物苯基庚三素和倍半萜酚塞尔诺醇决定。它们具有与塞尔比登类似的抗真菌活性谱,且活性接近念珠菌属、一些担子酵母、皮肤癣菌以及一些毛霉目真菌。