Lundgren E M, Cnattingius S, Jonsson B, Tuvemo T
Department of Women's and Children's Health, Uppsala University, Uppsala University Hospital, Sweden.
Acta Paediatr. 2003 Oct;92(10):1138-43.
To study the effect of size at birth on different dimensions of intellectual capacity.
The study comprised a population-based cohort including all male single births without congenital malformations in Sweden from 1973 to 1976, and conscripted before 1994 (n = 168 068). Information from the Swedish Birth Register was individually linked to the Swedish Conscript Register. The test of intellectual performance included four different dimensions: logical, spatial, theoretical and verbal capacity. These data were available for 80-86% of the males at conscription.
Compared with boys born appropriate for gestational age, males born small for gestational age (SGA) had an increased risk for subnormal performance in all four dimensions. Among males born SGA who were also of short adult stature at conscription, and in individuals born SGA with a head circumference <-- 2 SDS at birth, the risk of subnormal performance was most marked in the logical dimension (OR 1.52; CI 1.25-1.84 and 1.33; 1.15-1.55, respectively).
Being born small for gestational age is associated with increased risk of subnormal capacity in all four dimensions of intellectual performance. In SGA males, short adult stature, or a small head circumference at birth is especially associated with the risk of subnormal logical performance.
研究出生时的体型对智力能力不同维度的影响。
该研究纳入了一个基于人群的队列,包括1973年至1976年在瑞典出生且无先天性畸形的所有男性单胎婴儿,并于1994年前应征入伍者(n = 168068)。瑞典出生登记处的信息与瑞典应征入伍登记处进行了个体关联。智力表现测试包括四个不同维度:逻辑、空间、理论和语言能力。这些数据在80% - 86%的男性应征入伍时可获取。
与适于胎龄出生的男孩相比,小于胎龄(SGA)出生的男性在所有四个维度表现低于正常水平的风险增加。在出生时为SGA且应征入伍时成年身高也较矮的男性中,以及出生时为SGA且头围< - 2 SDS的个体中,逻辑维度表现低于正常水平的风险最为显著(OR分别为1.52;CI 1.25 - 1.84和1.33;1.15 - 1.55)。
小于胎龄出生与智力表现所有四个维度能力低于正常水平的风险增加相关。在SGA男性中,成年身高较矮或出生时头围较小尤其与逻辑表现低于正常水平的风险相关。