Huck J, Roumestant M L, Martinez J
UMR 5810, CNRS-LAPP Universités Montpellier I et II Place E, Bataillon 34095, Montpellier, Cédex, France.
J Pept Res. 2003 Dec;62(6):233-7. doi: 10.1046/j.1399-3011.2003.00080.x.
beta-N-tert-butyloxycarbonyl-N-carboxyanhydrides are very reactive beta-amino acid derivatives. They react cleanly and smoothly with different nucleophiles like aminoesters, enolates, N-methyl-d-glucamine, amidoximes to afford in good to excellent yields peptides, beta-amino ketocompounds, beta-aminosugars and functionalized disubstituted 1,2,4-oxadiazoles.
β-N-叔丁氧羰基-N-羧基酸酐是非常活泼的β-氨基酸衍生物。它们能与不同的亲核试剂如氨基酯、烯醇盐、N-甲基-D-葡萄糖胺、偕胺肟发生干净且顺利的反应，以良好至优异的产率得到肽、β-氨基酮化合物、β-氨基糖和功能化的二取代1,2,4-恶二唑。
Zotero 插件