Ciriaco Emilia, Píñera Pablo P, Díaz-Esnal Belén, Laurà Rosaria
Dipartimento di Morfologia, Biochimica, Fisiologia e Produzioni Animali, Università di Messina, Italy.
Microsc Res Tech. 2003 Dec 15;62(6):482-7. doi: 10.1002/jemt.10416.
The avian primary lymphoid organs, the thymus and the bursa of Fabricius, undergo age-dependent changes leading in some cases to the complete atrophy of the organ. Nevertheless, the timetable of the involutive process as well as the consequences in the structure and functionality of the organs vary largely in the time frame and structural changes among species. On the other hand, and in contrast with the large body of literature reporting the structural and functional changes in mammalian primary lymphoid organs, the age-dependent changes in avian thymus and bursa of Fabricius are scarce, fragmentary, and heterogeneous. This article reviews the current literature on this topic, and focuses primarily on the involution of the bursa of Fabricius.
禽类的主要淋巴器官,即胸腺和法氏囊,会经历与年龄相关的变化,在某些情况下会导致器官完全萎缩。然而,退化过程的时间表以及器官结构和功能方面的后果在不同物种的时间框架和结构变化中差异很大。另一方面,与大量报道哺乳动物主要淋巴器官结构和功能变化的文献形成对比的是,关于禽类胸腺和法氏囊随年龄变化的研究很少、很零散且不统一。本文综述了关于这一主题的现有文献,主要聚焦于法氏囊的退化。