向雏鸡脑室内注射蝇蕈醇、巴氯芬或哌啶酸会刺激蛋鸡品种（而非肉鸡品种）的雏鸡的采食量。
Intracerebroventricular injection of muscimol, baclofen or nipecotic acid stimulates food intake in layer-type, but not meat-type, chicks.
作者信息
Bungo Takashi, Izumi Tomofumi, Kawamura Kazuya, Takagi Tomo, Ueda Hiroshi, Furuse Mitsuhiro
机构信息
Laboratory of Animal Science, Department of Agrobiological Science, Faculty of Agriculture, Ehime University, 3-5-7 Tarumi, Matsuyama 790-8566, Japan.
出版信息
Brain Res. 2003 Dec 12;993(1-2):235-8. doi: 10.1016/j.brainres.2003.09.017.
This study was designed to compare the effects of muscimol (GABA(A) agonist), baclofen (GABA(B) agonist) and nipecotic acid (GABA uptake inhibitor) on food intake in two chicken strains (meat-type and layer-type chicks). The intracerebroventricular (ICV) injection of all GABA agents induced hyperphagia in layer-type chicks. However, in broiler chicks, there were similar tendencies with muscimol and nipecotic acid but not significantly different. Conversely, ICV injection of baclofen depressed feeding of broiler chicks. These results suggest that there are some differences in central GABAergic systems between these strains of chicks, but GABAergic systems have an important role in the regulation of food intake in neonatal chicks.
本研究旨在比较蝇蕈醇（GABA(A) 激动剂）、巴氯芬（GABA(B) 激动剂）和尼克酸（GABA 摄取抑制剂）对两种鸡品系（肉用型和蛋用型雏鸡）采食量的影响。向所有雏鸡脑室内（ICV）注射 GABA 剂均诱导蛋用型雏鸡出现摄食过量。然而，在肉用型雏鸡中，蝇蕈醇和尼克酸有类似趋势，但差异不显著。相反，脑室内注射巴氯芬会抑制肉用型雏鸡的采食。这些结果表明，这些品系雏鸡的中枢 GABA 能系统存在一些差异，但 GABA 能系统在新生雏鸡采食量的调节中起重要作用。
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