[发作性睡病犬。对人类发作性睡病的意义] - Suppr

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[Narcoleptic dogs. Significance for human narcolepsy].

作者信息

Schiefer J

机构信息

Neurologische Klinik, Universitätsklinikum Aachen, Aachen.

出版信息

Nervenarzt. 2003 Dec;74(12):1155-6. doi: 10.1007/s00115-003-1628-9.

DOI:10.1007/s00115-003-1628-9

PMID:14647919

Abstract

摘要

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[Narcoleptic dogs. Significance for human narcolepsy].

Nervenarzt. 2003 Dec;74(12):1155-6. doi: 10.1007/s00115-003-1628-9.

Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines.

Genome Res. 2001 Apr;11(4):531-9. doi: 10.1101/gr.gr-1610r.

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.

Cell. 1999 Aug 20;98(4):437-51. doi: 10.1016/s0092-8674(00)81973-x.

Narcolepsy: a key role for hypocretins (orexins).

Cell. 1999 Aug 20;98(4):409-12. doi: 10.1016/s0092-8674(00)81969-8.

Animal models of narcolepsy.

CNS Neurol Disord Drug Targets. 2009 Aug;8(4):296-308. doi: 10.2174/187152709788921717.

I. Mutation in the hypocretin (orexin) receptor 2 gene causes canine narcolepsy.

J Neurol. 1999 Oct;246(10):985-6. doi: 10.1007/s004150050501.

What we learned from narcolepsy of others.

J Mol Med (Berl). 2003 Feb;81(2):69-70. doi: 10.1007/s00109-002-0408-5.

Polymorphisms in hypocretin/orexin pathway genes and narcolepsy.

Neurology. 2001 Nov 27;57(10):1896-9. doi: 10.1212/wnl.57.10.1896.

Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors.

Curr Opin Neurobiol. 2002 Jun;12(3):339-45. doi: 10.1016/s0959-4388(02)00331-8.

Reply to 'Promotion of sleep by targeting the orexin system in rats, dogs and humans'.

Nat Med. 2007 May;13(5):525-6; author reply 526. doi: 10.1038/nm0507-525.

本文引用的文献

Functions of the orexinergic/hypocretinergic system.

Am J Physiol Cell Physiol. 2002 Dec;283(6):C1567-91. doi: 10.1152/ajpcell.00055.2002.

CSF hypocretin/orexin levels in narcolepsy and other neurological conditions.

Neurology. 2001 Dec 26;57(12):2253-8. doi: 10.1212/wnl.57.12.2253.

Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines.

Genome Res. 2001 Apr;11(4):531-9. doi: 10.1101/gr.gr-1610r.

Sleepy dogs don't lie: a genetic disorder informative about sleep.

Genome Res. 2001 Apr;11(4):509-11. doi: 10.1101/gr.184301.

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains.

Nat Med. 2000 Sep;6(9):991-7. doi: 10.1038/79690.

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene.

Cell. 1999 Aug 6;98(3):365-76. doi: 10.1016/s0092-8674(00)81965-0.

Breeding history of the Stanford colony of narcoleptic dogs.

Vet Rec. 1998 Jan 10;142(2):31-6. doi: 10.1136/vr.142.2.31.

HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients.

Sleep. 1997 Nov;20(11):1012-20.

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):322-7. doi: 10.1073/pnas.95.1.322.

Sleep fragmentation in canine narcolepsy.

Sleep. 1986;9(1 Pt 2):116-9. doi: 10.1093/sleep/9.1.116.

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[Narcoleptic dogs. Significance for human narcolepsy].

作者信息

Schiefer J

机构信息

Neurologische Klinik, Universitätsklinikum Aachen, Aachen.

出版信息

Nervenarzt. 2003 Dec;74(12):1155-6. doi: 10.1007/s00115-003-1628-9.

DOI:10.1007/s00115-003-1628-9

PMID:14647919

Abstract

摘要

相似文献

[Narcoleptic dogs. Significance for human narcolepsy].

Nervenarzt. 2003 Dec;74(12):1155-6. doi: 10.1007/s00115-003-1628-9.

Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines.

Genome Res. 2001 Apr;11(4):531-9. doi: 10.1101/gr.gr-1610r.

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.

Cell. 1999 Aug 20;98(4):437-51. doi: 10.1016/s0092-8674(00)81973-x.

Narcolepsy: a key role for hypocretins (orexins).

Cell. 1999 Aug 20;98(4):409-12. doi: 10.1016/s0092-8674(00)81969-8.

Animal models of narcolepsy.

CNS Neurol Disord Drug Targets. 2009 Aug;8(4):296-308. doi: 10.2174/187152709788921717.

I. Mutation in the hypocretin (orexin) receptor 2 gene causes canine narcolepsy.

J Neurol. 1999 Oct;246(10):985-6. doi: 10.1007/s004150050501.

What we learned from narcolepsy of others.

J Mol Med (Berl). 2003 Feb;81(2):69-70. doi: 10.1007/s00109-002-0408-5.

Polymorphisms in hypocretin/orexin pathway genes and narcolepsy.

Neurology. 2001 Nov 27;57(10):1896-9. doi: 10.1212/wnl.57.10.1896.

Sleep, feeding, and neuropeptides: roles of orexins and orexin receptors.

Curr Opin Neurobiol. 2002 Jun;12(3):339-45. doi: 10.1016/s0959-4388(02)00331-8.

Reply to 'Promotion of sleep by targeting the orexin system in rats, dogs and humans'.

Nat Med. 2007 May;13(5):525-6; author reply 526. doi: 10.1038/nm0507-525.

本文引用的文献

Functions of the orexinergic/hypocretinergic system.

Am J Physiol Cell Physiol. 2002 Dec;283(6):C1567-91. doi: 10.1152/ajpcell.00055.2002.

CSF hypocretin/orexin levels in narcolepsy and other neurological conditions.

Neurology. 2001 Dec 26;57(12):2253-8. doi: 10.1212/wnl.57.12.2253.

Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines.

Genome Res. 2001 Apr;11(4):531-9. doi: 10.1101/gr.gr-1610r.

Sleepy dogs don't lie: a genetic disorder informative about sleep.

Genome Res. 2001 Apr;11(4):509-11. doi: 10.1101/gr.184301.

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains.

Nat Med. 2000 Sep;6(9):991-7. doi: 10.1038/79690.

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene.

Cell. 1999 Aug 6;98(3):365-76. doi: 10.1016/s0092-8674(00)81965-0.

Breeding history of the Stanford colony of narcoleptic dogs.

Vet Rec. 1998 Jan 10;142(2):31-6. doi: 10.1136/vr.142.2.31.

HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients.

Sleep. 1997 Nov;20(11):1012-20.

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):322-7. doi: 10.1073/pnas.95.1.322.

Sleep fragmentation in canine narcolepsy.

Sleep. 1986;9(1 Pt 2):116-9. doi: 10.1093/sleep/9.1.116.