MAGIC凝胶中磁化传递的定量研究。
A quantitative study of magnetization transfer in MAGIC gels.
作者信息
Gochberg Daniel F, Fong Peter M, Gore John C
机构信息
Department of Radiology and Radiological Sciences, Vanderbilt Medical School, Institute of Imaging Science, Vanderbilt University, 1161 21st Avenue S, R-1302 MCN, Nashville, TN 37232-2675, USA.
出版信息
Phys Med Biol. 2003 Nov 7;48(21):N277-82. doi: 10.1088/0031-9155/48/21/n01.
Magnetization transfer (MT) has been measured quantitatively as a function of radiation dose in MAGIC polymer gels. The MT rates between the free and immobile macromolecular proton pools (kmr and kfm), and the ratio of the sizes of these coupled proton pools (Pm/Pf), were measured by analysing the response to an inversion recovery sequence. While pm/pf increases linearly with dose, the fast MT rate kmf also increases with dose, unlike previous measurements in BANG gels. This dependence of kmf on dose suggests there are additional factors that modify spin exchange in MAGIC gels as irradiation occurs.
在MAGIC聚合物凝胶中，已定量测量了作为辐射剂量函数的磁化传递（MT）。通过分析对反转恢复序列的响应，测量了自由和固定大分子质子池之间的MT速率（kmr和kfm）以及这些耦合质子池大小的比率（Pm/Pf）。虽然pm/pf随剂量呈线性增加，但与之前在BANG凝胶中的测量结果不同，快速MT速率kmf也随剂量增加。kmf对剂量的这种依赖性表明，在辐照发生时，存在其他因素会改变MAGIC凝胶中的自旋交换。
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