Zhong Ruiqin, Ye Zheng-Hua
Department of Plant Biology, University of Georgia, Athens, GA 30602, USA.
Trends Plant Sci. 2003 Dec;8(12):565-8. doi: 10.1016/j.tplants.2003.10.003.
The function of glycosyltransferases (GTs) from family GT47 was first identified in animal exostosins as beta-glucuronyltransferase involved in the synthesis of heparan sulfate. Two recent papers report the functions of two plant members in this family as a pectin beta-glucuronyltransferase and a xyloglucan beta-galactosyltransferase. These findings greatly extend our understanding of the biological functions of family GT47 and also represent an important leap toward the molecular dissection of cell wall biosynthesis.
来自GT47家族的糖基转移酶(GTs)的功能最初在动物外生骨疣蛋白中被鉴定为参与硫酸乙酰肝素合成的β-葡糖醛酸基转移酶。最近的两篇论文报道了该家族中两个植物成员作为果胶β-葡糖醛酸基转移酶和木葡聚糖β-半乳糖基转移酶的功能。这些发现极大地扩展了我们对GT47家族生物学功能的理解,也代表了在细胞壁生物合成分子剖析方面的重要飞跃。