Fang Di, Meyer Roger E
Division of Biomedical and Health Sciences Research, the Association of American Medical Colleges, Washington, DC, USA.
Acad Med. 2003 Dec;78(12):1271-80. doi: 10.1097/00001888-200312000-00017.
To assess the effect of Howard Hughes Medical Institute's (HHMI) two one-year research training programs for medical students on the awardees' research careers.
Awardees of the HHMI Cloister Program who graduated between 1987 and 1995 and awardees of the HHMI Medical Fellows Program who graduated between 1991 and 1995 were compared with unsuccessful applicants to the programs and MD-PhD students who graduated during the same periods. Logistic regression analyses were conducted to assess research career outcomes while controlling for academic and demographic variables that could affect selection to the programs.
Participation in both HHMI programs increased the likelihood of receiving National Institutes of Health postdoctoral support. Participation in the Cloister Program also increased the likelihood of receiving a faculty appointment with research responsibility at a medical school. In addition, awardees of the Medical Fellows Program were not significantly less likely than Medical Scientist Training Program (MSTP) and non-MSTP MD-PhD program participants to receive a National Institutes of Health postdoctoral award, and awardees of the Cloister Program were not significantly less likely than non-MSTP MD-PhD students to receive a faculty appointment with research responsibility. Women and underrepresented minority students were proportionally represented among awardees of the two HHMI programs whereas they were relatively underrepresented in MD-PhD programs.
The one-year intensive research training supported by the HHMI training programs appears to provide an effective imprinting experience on medical students' research careers and to be an attractive strategy for training physician-scientists.
评估霍华德·休斯医学研究所（HHMI）为医学生提供的两个为期一年的研究培训项目对获奖者研究职业生涯的影响。
将1987年至1995年间毕业的HHMI修道院项目获奖者、1991年至1995年间毕业的HHMI医学研究员项目获奖者与这些项目的未成功申请者以及同期毕业的医学博士-哲学博士（MD-PhD）学生进行比较。进行逻辑回归分析以评估研究职业成果，同时控制可能影响项目入选的学术和人口统计学变量。
参与HHMI的两个项目均增加了获得美国国立卫生研究院博士后支持的可能性。参与修道院项目也增加了在医学院获得有研究职责的教职任命的可能性。此外，医学研究员项目的获奖者获得美国国立卫生研究院博士后奖励的可能性并不显著低于医学科学家培训项目（MSTP）和非MSTP的MD-PhD项目参与者，修道院项目的获奖者获得有研究职责的教职任命的可能性并不显著低于非MSTP的MD-PhD学生。在HHMI的两个项目获奖者中，女性和代表性不足的少数族裔学生所占比例合理，而在MD-PhD项目中他们的代表性相对不足。
HHMI培训项目支持的为期一年的强化研究培训似乎为医学生的研究职业生涯提供了有效的烙印体验，并且是培养医师科学家的一种有吸引力的策略。
