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[囊性纤维化的抗炎治疗]

[Anti-inflammatory therapy in cystic fibrosis].

作者信息

Derelle J

机构信息

Hôpital d'Enfants, rue Morvan, 54511 Vandaeuvre-les-Nancy, France.

出版信息

Arch Pediatr. 2003 Sep;10 Suppl 2:370s-375s. doi: 10.1016/s0929-693x(03)90055-8.

Abstract

Cystic fibrosis lung inflammation is early, sustained and severe and would justify an anti-inflammatory treatment. At present, the inhaled corticosteroid treatment did not give evidence of efficacy, contrary to the oral presentation, but at the cost of side effects. Azithromycin gives more encouraging results with a good tolerance. New molecules are in the process of validation.

摘要

囊性纤维化肺部炎症出现早、持续且严重,因此有必要进行抗炎治疗。目前,吸入性糖皮质激素治疗未显示出疗效,与口服给药情况相反,且伴有副作用。阿奇霉素的治疗效果更令人鼓舞,耐受性良好。新的药物分子正在进行验证。

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