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[从普通外科医生角度看急性肢体缺血。需要多少血管外科知识?]

[Acute limb ischemia from the general surgeon's point of view. How much knowledge of vascular surgery is necessary?].

作者信息

Kopp R, Weidenhagen R, Hornung H, Jauch K W, Lauterjung L

机构信息

Chirurgische Klinik und Poliklinik, Klinikum Grosshadern, Universität München,

出版信息

Chirurg. 2003 Dec;74(12):1090-102. doi: 10.1007/s00104-003-0773-9.

Abstract

The diagnosis of acute peripheral ischemia can be obtained based on clinical presentation, inspection, and palpation of the affected extremity. Unfractionated heparin as a single shot is immediately given followed by continuous infusion when diagnosis is clinically evident and contraindications are excluded. Thromboembolectomy using a Fogarty catheter is immediately performed in patients with evidence of arterial embolization and signs of advanced ischemia (TASC IIb/III) followed by intraoperative angiography. Patients with evidence of arterial thrombosis require urgent angiography followed by thrombectomy and probably subsequent endovascular or surgical interventions and vascular reconstruction. For patients with moderate ischemia (TASC IIa), initial diagnostic angiography is recommended followed by primary thrombectomy with subsequent intraoperative angiography and immediate endovascular or operative treatment of remaining vascular problems. As an alternative therapeutic option initial catheter-guided local thrombolysis can be performed in selected patients with the intention of subsequent limb revascularization or unmasking relevant vessel alterations leading to specific endovascular or surgically performed vascular reconstruction. Possible development of muscle ischemia because of increased compartment pressure should be considered and fasciotomy performed when indicated. Primary amputation of the severely ischemic limb after initial thrombectomy might be recommended in patients with life-threatening organ failure related to muscle necrosis.

摘要

急性外周缺血的诊断可基于临床表现、对患肢的检查和触诊来做出。一旦临床诊断明确且排除禁忌证,立即单次注射普通肝素,随后持续输注。对于有动脉栓塞证据且存在严重缺血体征(TASC IIb/III)的患者,立即使用Fogarty导管进行血栓切除术,随后进行术中血管造影。有动脉血栓形成证据的患者需要紧急血管造影,然后进行血栓切除术,可能随后还需要进行血管内或外科干预以及血管重建。对于中度缺血(TASC IIa)的患者,建议先进行初步诊断性血管造影,然后进行原发性血栓切除术,随后进行术中血管造影,并对剩余的血管问题立即进行血管内或手术治疗。作为一种替代治疗选择,对于选定的患者,可首先进行导管引导下局部溶栓,目的是随后实现肢体血运重建或发现导致特定血管内或手术血管重建的相关血管改变。应考虑因筋膜间室压力升高导致肌肉缺血的可能性,并在有指征时进行筋膜切开术。对于与肌肉坏死相关的危及生命的器官衰竭患者,在初次血栓切除术后,可能建议对严重缺血的肢体进行一期截肢。

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