Zwaveling-Soonawala N, Spanjaard L, van de Wetering M, Winterberg D H
Afd. Kindergeneeskunde, Academisch Medisch Centrum/Universiteit van Amsterdam, locatie Emma Kinderziekenhuis, Amsterdam.
Ned Tijdschr Geneeskd. 2003 Nov 29;147(48):2386-9.
A diagnosis of intracranial actinomycosis was made in a 9-year-old boy with headache, cranial nerve dysfunction and ataxia. Poor dental hygiene leading to caries and an inflammation in his right upper jaw probably was the cause of cervicofacial actinomycosis with intracranial extension. A full recovery was achieved by treatment with benzylpenicillin. Actinomyces is a gram-positive bacterium belonging to the endogenous flora of the mucous membranes of the oropharynx, gastrointestinal tract, and female genital tract. Disruption of the mucous membrane is the portal of entry for an extremely destructive infective process that is effectively treated with penicillin. Good orodental hygiene is important for the prevention of actinomycosis.
一名9岁男孩因头痛、颅神经功能障碍和共济失调被诊断为颅内放线菌病。口腔卫生差导致龋齿和右上颌炎症，这可能是导致颈面部放线菌病并向颅内蔓延的原因。通过苄星青霉素治疗实现了完全康复。放线菌是一种革兰氏阳性菌，属于口咽、胃肠道和女性生殖道黏膜的内源性菌群。黏膜破裂是一种极具破坏性感染过程的入口，青霉素可有效治疗该感染过程。保持良好的口腔卫生对预防放线菌病很重要。
