Dufourcq Pascale, Rastegar Sepand, Strähle Uwe, Blader Patrick
Centre de Biologie du Développement UMR5547, bât. 4R3, Université Paul Sabatier, 118 route de Narbonne, 31062 Toulouse, France.
Gene Expr Patterns. 2004 Jan;4(1):53-7. doi: 10.1016/s1567-133x(03)00148-0.
We describe the isolation of zebrafish growth factor independent 1 (gfi1) and present an analysis of its pattern of expression during early development. As with its murine homologue, gfi1 expression is detected in the ganglion cells of the neural retina and in developing hair cells of the ear. In keeping with a role in the development of sensory hair cells, gfi1 is also expressed in neuromasts of the anterior and posterior lateral line system. Finally, gfi1 is expressed in the developing epithalamus in the dorsal diencephalon where its transcription is restricted to the parapineal.
我们描述了斑马鱼生长因子独立1(gfi1)的分离,并对其在早期发育过程中的表达模式进行了分析。与其小鼠同源物一样,gfi1在神经视网膜的神经节细胞和内耳发育中的毛细胞中被检测到。与在感觉毛细胞发育中的作用一致,gfi1也在前庭和后外侧线系统的神经丘中表达。最后,gfi1在背侧间脑发育中的上丘脑表达,其转录仅限于松果旁体。