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既往主动脉手术后的胸腹主动脉瘤修复术。

Thoracoabdominal aortic aneurysm repair after prior aortic surgery.

作者信息

Lombardi Joseph V, Carpenter Jeffrey P, Pochettino Alberto, Sonnad Seema S, Bavaria Joseph E

机构信息

Department of Surgery, University of Pennsylvania School of Medicine, University Hospital, 4 Silverstein, 3400 Spruce Street, Philadelphia, PA 19104, USA.

出版信息

J Vasc Surg. 2003 Dec;38(6):1185-90. doi: 10.1016/j.jvs.2003.08.034.

Abstract

PURPOSE

The purpose of this study was to determine whether the morbidity and mortality of surgery for thoracoabdominal aortic aneurysm (TAAA) in patients with prior aortic surgery are increased.

METHODS

The results for all patients undergoing operation for TAAA at a single institution were reviewed.

RESULTS

Over a 10-year interval, 279 patients (136 women and 143 men) underwent aortic replacement for TAAA. The mean patient age was 68 years (range, 34-90). The extent of aortic replacement was relatively evenly distributed: type I (91), type II (54), type III (78), or type IV (56). Of these 279 patients, 76 (27%) had undergone prior aortic surgery. Prior infrarenal AAA was the most common prior procedure (56, 20%). Reoperation for prior failed TAAA repair was performed in 20 (7%) patients. A history of Marfan syndrome was highly associated with the need for remedial TAAA procedures (P <.0001). Overall 30-day mortality was 11.4% (32). Mortality was independent of prior aortic surgery (P =.98), prior AAA (P =.84), prior TAAA (P =.61), and gender (P =.18). Postoperative complications were seen in 67 (24%) patients and were more likely in patients who had undergone prior AAA surgery (P =.008). TAAA repair in patients with recurrent TAAA was not associated with higher morbidity (P =.33). Paraplegia (10) occurred in type I (3), type II (2), and type III (5) aneurysms but not in type IV (0), and its development was associated with higher mortality (P =.01). Prior aortic surgery was not found to be predictive of paraplegia (P =.90), although 30% of patients who developed paraplegia had a history of prior AAA repair.

CONCLUSIONS

Aortic reoperation for TAAA is required in a significant number of patients, particularly those with Marfan syndrome. Therefore, ongoing surveillance of the residual aorta is mandatory. Postoperative complications are more likely to occur in patients after prior infrarenal aortic replacement, but mortality is not significantly increased. Special technical considerations exist for remedial procedures after failed TAAA repair to provide protection for the spinal cord, kidneys, and viscera. Patients with failed TAAA procedures or progression of aneurysmal extent should be offered reoperation when indicated.

摘要

目的

本研究旨在确定既往接受过主动脉手术的患者行胸腹主动脉瘤(TAAA)手术时,其发病率和死亡率是否会升高。

方法

回顾了在单一机构接受TAAA手术的所有患者的结果。

结果

在10年期间,279例患者(136例女性和143例男性)接受了TAAA主动脉置换术。患者平均年龄为68岁(范围34 - 90岁)。主动脉置换范围分布相对均匀:I型(91例)、II型(54例)、III型(78例)或IV型(56例)。在这279例患者中,76例(27%)既往接受过主动脉手术。既往肾下腹主动脉瘤是最常见的既往手术(56例,20%)。20例(7%)患者因既往TAAA修复失败而再次手术。马凡综合征病史与补救性TAAA手术需求高度相关(P <.0001)。总体30天死亡率为11.4%(32例)。死亡率与既往主动脉手术(P =.98)、既往腹主动脉瘤(P =.84)、既往TAAA(P =.61)及性别(P =.18)无关。67例(24%)患者出现术后并发症,既往接受过腹主动脉瘤手术的患者更易发生(P =.008)。复发性TAAA患者的TAAA修复与较高发病率无关(P =.33)。截瘫发生在I型(3例)、II型(2例)和III型(5例)动脉瘤患者中,IV型(0例)未发生,其发生与较高死亡率相关(P =.01)。虽然30%发生截瘫的患者有既往腹主动脉瘤修复史,但未发现既往主动脉手术可预测截瘫(P =.90)。

结论

相当一部分患者需要行TAAA主动脉再次手术,尤其是马凡综合征患者。因此,对残余主动脉进行持续监测是必要的。既往肾下腹主动脉置换术后患者更易发生术后并发症,但死亡率未显著增加。对于TAAA修复失败后的补救手术,存在特殊技术考量以保护脊髓、肾脏和内脏。TAAA手术失败或动脉瘤范围进展的患者,如有指征应考虑再次手术。

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