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在一名异基因骨髓移植受者中由球毛壳菌引起的暗色丝孢霉病。

Phaeohyphomycosis caused by Chaetomium globosum in an allogeneic bone marrow transplant recipient.

作者信息

Teixeira A B A, Trabasso P, Moretti-Branchini M L, Aoki F H, Vigorito A C, Miyaji M, Mikami Y, Takada M, Schreiber A Z

机构信息

Clinical Pathology Department, Universidade Estadual de Campinas-UNICAMP, Brazil.

出版信息

Mycopathologia. 2003;156(4):309-12. doi: 10.1023/b:myco.0000003563.29320.95.

Abstract

Bone marrow transplant recipients are highly susceptible to opportunistic fungal infections. This is the report, of the first case of a Chaetomium systemic infection described in Brazil. A 34 year-old patient with chronic myeloid leukemia underwent an allogeneic sibling matched bone marrow transplant. Seven months later, he developed systemic infection with enlargement of the axillary and cervical lymph nodes. Culture of the aspirates from both lymph nodes yielded Chaetomium globosum. The infection was successfully treated with amphotericin B. The increasing population of immunosupressed patients requires a careful microbiologic investigation for uncommon fungal infections.

摘要

骨髓移植受者极易感染机会性真菌感染。这是巴西首例关于毛壳菌全身感染病例的报告。一名34岁的慢性髓性白血病患者接受了同胞全相合异基因骨髓移植。七个月后,他出现了全身感染,腋窝和颈部淋巴结肿大。从两个淋巴结抽出液的培养物中分离出了球毛壳菌。感染用两性霉素B成功治愈。免疫抑制患者数量的增加需要对罕见真菌感染进行仔细的微生物学调查。

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