Saucedo de la Llata Eric, Moraga Sánchez María Rosa, Batiza Resendiz Víctor, Galache Vega Pedro, Santos Haliscak Roberto, Hernández Ayup Samuel
Instituto para el Estudio de la Concepción Humana (IECH), Monterrey, N.L.-Centro de Ginecología y Obstetricia de Monterrey, S.A. (CGOMSA).
Ginecol Obstet Mex. 2003 Sep;71:455-9.
To determine the influence of sperm morphology, according to WHO criteria, on pregnancy rates of couples who were submitted to intra-uterine insemination (IUI).
Retrospective study that included 787 IUI cycles performed in the Instituto para el Estudio de la Concepción Humana in Monterrey, Mexico, from January to December 2002. Main diagnosis were anovulation, male factor, endometriosis, and cervical factor. All patients were allocated into a controlled ovarian hyperstimulation protocol with either clomiphene citrate, menotropins and/or recombinant FSH.
A total of 115 pregnancies were achieved (pregnancy rate per cycle of 14.61%). When seminal parameters were analyzed as independent factors it was found that a motility less than 10%, total motile count after sperm preparation less than 1 million/ml and sperm motility less than 20% had a pregnancy rate of zero.
Patients with normal sperm forms less than 20% according to WHO criteria have no benefit with the IUI and these patients should be canalized to ART.
根据世界卫生组织（WHO）标准，确定精子形态对接受宫内人工授精（IUI）夫妇妊娠率的影响。
回顾性研究，纳入了2002年1月至12月在墨西哥蒙特雷人类受孕研究机构进行的787个IUI周期。主要诊断为无排卵、男性因素、子宫内膜异位症和宫颈因素。所有患者均采用克罗米芬、促性腺激素和/或重组促卵泡激素进行控制性卵巢过度刺激方案。
共实现115例妊娠（每个周期妊娠率为14.61%）。当将精液参数作为独立因素分析时，发现活力低于10%、精子制备后总活动计数低于100万/ml以及精子活力低于20%的妊娠率为零。
根据WHO标准，精子形态正常的患者少于20%，接受IUI无益处，这些患者应转诊至辅助生殖技术（ART）。
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