Baumann Thomas K, Burchiel Kim J
Department of Neurological Surgery, L472, Oregon Health and Science University, Portland, OR 97239-3098, USA.
J Neurosci Methods. 2004 Jan 15;132(1):19-24. doi: 10.1016/j.jneumeth.2003.08.016.
The etiology of trigeminal neuralgia appears to be vascular compression of the nerve at the root entry zone. However, the physiologic mechanism of trigeminal neuralgia remains uncertain. To gain insight into the pathophysiology of the disorder, we developed a method for intraoperative microneurographic recordings from the trigeminal ganglion of patients with trigeminal neuralgia. The recordings are performed immediately prior to standard percutaneous trigeminal gangliolysis for pain relief. Spontaneous or evoked single- and multi-unit action potential activity can be recorded and the location of receptive fields determined. The method should facilitate the testing of hypotheses concerning the origin of this unique pain disorder.
三叉神经痛的病因似乎是神经根入区神经受到血管压迫。然而，三叉神经痛的生理机制仍不明确。为深入了解该疾病的病理生理学，我们开发了一种在患有三叉神经痛的患者三叉神经节进行术中微神经图记录的方法。这些记录在进行标准经皮三叉神经节溶解术以缓解疼痛之前立即进行。可以记录自发或诱发的单单位和多单位动作电位活动，并确定感受野的位置。该方法应有助于检验关于这种独特疼痛疾病起源的假设。
Zotero 插件