Lorenzana L, Cabezudo J M, Porras L F, Polaina M, Rodriguez-Sanchez J A, Garcia-Yagüe L M
Seccion de Neurocirugía, Hospital Universitario Infanta Cristina, Universidad de Extremadura, Badajoz, Spain.
Neurosurgery. 1992 Dec;31(6):1108-11; discussion 1111-2. doi: 10.1227/00006123-199212000-00019.
The case of a young woman with focal dystonia of the hand due to a cavernous angioma of the basal ganglia is presented. The lesion involved the anterior third of the lentiform nucleus and a large portion of white matter anterior to this nucleus and lateral to the head of the caudate, as shown by magnetic resonance imaging; it was completely removed through a computed tomography-assisted stereotactic craniotomy by microsurgical technique, resulting in the cure of the patient. These facts support the pathophysiological hypothesis of a disruption of the striatopallidothalamic projection to the premotor cortex as the cause of symptomatic dystonia. A review of the reported cases of cavernous angiomas of the deep cerebral gray nuclei shows that this is the first case of cavernous angioma associated with movement disorder.
本文报告了一名年轻女性因基底节海绵状血管瘤导致手部局灶性肌张力障碍的病例。磁共振成像显示，病变累及豆状核前三分之一以及该核前方和尾状核头部外侧的大部分白质；通过计算机断层扫描辅助立体定向开颅显微手术将其完全切除，患者得以治愈。这些事实支持了纹状体苍白球丘脑投射至运动前皮质中断是症状性肌张力障碍病因的病理生理假说。对已报道的大脑深部灰质核团海绵状血管瘤病例的回顾表明，这是首例与运动障碍相关的海绵状血管瘤病例。
