丙泊酚-咪达唑仑-芬太尼静脉输注麻醉用于猪的实验性手术。

Intravenous infusion anesthesia with Propofol-Midazolam-fentanyl for experimental surgery in swine.

作者信息

Kaiser Gernot M, Frühauf Nils R, Zhang Hongwei, Westermann Stephanie, Bolle Ines, Oldhafer Karl J, Broelsch Christoph E

机构信息

Department of General Surgery and Transplantation, University Hospital, Essen, Germany.

出版信息

J Invest Surg. 2003 Nov-Dec;16(6):353-7. doi: 10.1080/08941930390250223.

DOI:10.1080/08941930390250223

PMID:14708548

Abstract

There is a need for prolonged anesthesia procedures in experimental surgery. Animals in this study received fentanyl, Midazolam, and Propofol administered by continuous intravenous infusion for anesthesia along with controlled ventilation. Time of anesthesia was 413 +/- 95 min. Animals could be extubated 20 +/- 12 min after operation. Animals recovered completely from anesthesia by day 1 after surgery with almost normal physical activity. This study clearly shows that intravenous infusion anesthesia is safe and easy to handle in prolonged anesthesia for experimental surgery in swine. This anesthetic protocol can also be used for intraoperative transportation.

摘要

在实验性手术中需要进行长时间的麻醉程序。本研究中的动物接受芬太尼、咪达唑仑和丙泊酚通过持续静脉输注进行麻醉，并进行控制通气。麻醉时间为413±95分钟。动物可在术后20±12分钟拔管。术后第1天动物从麻醉中完全恢复，身体活动几乎正常。本研究清楚地表明，静脉输注麻醉在猪的实验性手术长时间麻醉中是安全且易于操作的。这种麻醉方案也可用于术中转运。