Iwen Peter C
Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center Omaha, NE 68198-6495, USA.
Clin Lab Med. 2003 Dec;23(4):781-99. doi: 10.1016/s0272-2712(03)00082-9.
A major goal of molecular testing is to develop a cost-effective as well as sensitive and specific assay that can detect microbial DNA in clinical samples early in the course of disease. Additionally, the ability to analyze the genetic relatedness of fungi on a timelier basis using molecular methods will have a positive impact on epidemiologic investigating. As technology advances, it seems apparent that commercially available molecular assays will become available in the near future for the management of patients with suspected fungal infections.
分子检测的一个主要目标是开发一种经济高效且灵敏特异的检测方法,该方法能够在疾病进程早期检测临床样本中的微生物DNA。此外,使用分子方法更及时地分析真菌的遗传相关性的能力将对流行病学调查产生积极影响。随着技术的进步,在不久的将来,用于疑似真菌感染患者管理的商用分子检测方法似乎会问世。