Merzel José, Nunes Silvana F, Novaes Pedro D
Department of Morphology, Faculty of Odontology of Piracicaba, State University of Campinas (Unicamp), PO Box 52, 13414-903, SP, Piracicaba, Brazil.
Arch Oral Biol. 2004 Mar;49(3):209-16. doi: 10.1016/j.archoralbio.2003.09.009.
Previous work has indicated that the enamel-related periodontium (ERP) has a role in the eruptive process of the rat lower incisor. By combining partial damage of this tissue with resection of the odontogenic organ, we examined the effect of the damage on subsequent incisor eruption. The connective tissue of the enamel-related periodontium was regenerated in less than 2 weeks, showing morphology close to normal. The injured part of the enamel organ was neither regenerated nor repaired, and a cement-like tissue, continuous with the true acellular cement, was formed on the denuded enamel. Before tooth exfoliation, the operated teeth erupted at a slower rate compared with root-resected and sham-operated incisors, probably because of the absence of a substantial part of the enamel organ due to surgical damage. As with the coronal dental follicle and the enamel organ in rat molars, the enamel-related periodontium and the enamel organ of rat incisors may have some control on their eruptive process.
先前的研究表明，牙釉质相关牙周组织（ERP）在大鼠下切牙的萌出过程中发挥作用。通过将该组织的部分损伤与牙源性器官切除相结合，我们研究了这种损伤对后续切牙萌出的影响。牙釉质相关牙周组织的结缔组织在不到2周的时间内再生，形态接近正常。牙釉质器官的受损部分既未再生也未修复，在裸露的牙釉质上形成了与真正的无细胞牙骨质连续的类牙骨质组织。在牙齿脱落之前，与牙根切除和假手术的切牙相比，手术牙的萌出速度较慢，这可能是由于手术损伤导致牙釉质器官的大部分缺失。与大鼠磨牙的冠状牙囊和牙釉质器官一样，大鼠切牙的牙釉质相关牙周组织和牙釉质器官可能对其萌出过程有一定的控制作用。
