André Marc, Delèvaux Isabelle, Amoura Zahir, Corbi Pierre, Courthaliac Christophe, Aumaître Olivier, Piette Jean-Charles
Gabriel Montpied Hospital, University Hospital of Clermont-Ferrand, Clermont-Ferrand, France.
Arthritis Rheum. 2004 Jan;50(1):183-6. doi: 10.1002/art.11435.
Ovarian vein thrombosis (OVT) is an unusual condition mainly observed during the postpartum period. It has not been reported to date in the antiphospholipid syndrome. Two female patients with definite antiphospholipid syndrome, ages 33 years and 73 years, were diagnosed as having OVT by computed tomography (CT) scan, according to the radiologic criteria described by Zerhouni et al. In 1 of the women, the left vein was affected by OVT, while in the other woman, the right vein was affected. One of the patients had a pulmonary embolism; the diagnosis of OVT was established after she underwent a cesarean section and a right atrium thrombectomy. The other patient had no vascular manifestations. OVT was asymptomatic in both patients. Searches for associated thrombophilic states yielded negative results. With the continuation of anticoagulation therapy, the 2 patients have remained in good condition. Resolution of the OVT was observed in the patient who underwent a CT scan during followup. To our knowledge, this is the first report of OVT occurring in the antiphospholipid syndrome. Given that it may develop in the absence of pelvic clinical manifestations, this complication may be underdiagnosed.
卵巢静脉血栓形成（OVT）是一种主要在产后期间观察到的罕见病症。迄今为止，抗磷脂综合征中尚未有相关报道。两名确诊为抗磷脂综合征的女性患者，年龄分别为33岁和73岁，根据Zerhouni等人描述的放射学标准，通过计算机断层扫描（CT）被诊断为患有OVT。其中一名女性患者的左静脉受OVT影响，而另一名女性患者的右静脉受影响。其中一名患者发生了肺栓塞；在她接受剖宫产和右心房血栓切除术后确诊为OVT。另一名患者没有血管表现。两名患者的OVT均无症状。对相关血栓形成倾向状态的检查结果为阴性。随着抗凝治疗的持续，两名患者情况良好。在随访期间接受CT扫描的患者中观察到OVT消退。据我们所知，这是抗磷脂综合征中发生OVT的首例报告。鉴于它可能在没有盆腔临床表现的情况下发生，这种并发症可能未被充分诊断。
