Lippincott-Schwartz J
Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Trends Cell Biol. 1993 Mar;3(3):81-8. doi: 10.1016/0962-8924(93)90078-f.
Membrane traffic between the endoplasmic reticulum and Golgi apparatus is a highly regulated process that uses distinct anterograde and retrograde pathways. These pathways link two organelles that together function as a dynamic membrane system specialized for the biosynthesis and sorting of membrane to be used throughout the cell. The nature and underlying biochemical control of membrane transport along these pathways is thought to be tied to a common regulatory system involving assembly and disassembly of cytosolic proteins on membranes.
内质网与高尔基体之间的膜运输是一个高度受调控的过程,它利用不同的顺行和逆行途径。这些途径连接了两个细胞器,它们共同构成一个动态膜系统,专门用于生物合成和分选供整个细胞使用的膜。沿这些途径的膜运输的性质和潜在生化控制被认为与一个涉及膜上胞质蛋白组装和拆卸的共同调节系统相关。