Kiyota Kazuya
Tertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital.
Chudoku Kenkyu. 2003 Oct;16(4):453-8.
A-55-year-old man ingested unknown amount of snail poison bait containing metaldehyde. He was mentally retarded and presented pica. On admission, his vital sign was stable, and the extremeties were spastic. Then, gastric lavage was unsuccessful because of massive unbited food. Activated charcoal and cathartic were administrated. On the next day, general convulsion occurred and respiratory distress advanced, so he was intubated. On the 3rd day, infiltration shadow appeared on chest roentogenogram and, his respiration was assisted mechanically. Thereby, acute lung injury advanced regardless of tracheostomy, kinetic therapy, antibiotics and steroid pulse therapy. He died of respiratory failure on the 33rd day. Serum test showed HBs and HBe antigen, CT scan revealed ascites and splenomegaly; the clinical course might be worsened by liver cirrhosis. HPLC revealed metaldehyde in the serum (total 80.6 microg/ml). He ingested 2.7 g of metaldehyde maximally estimated. Although Japan Poison Information Center reported that snail poison bait poisoning is often in dogs in Japan, human poisoning is rare.
一名55岁男性摄入了未知量的含有聚乙醛的杀螺诱饵。他智力发育迟缓且有异食癖。入院时,他生命体征稳定,四肢痉挛。由于大量未消化食物,洗胃未成功。给予了活性炭和泻药。第二天,出现全身惊厥且呼吸窘迫加重,于是对他进行了插管。第三天,胸部X线片出现浸润影,对其进行了机械辅助呼吸。因此,尽管进行了气管切开术、动态治疗、抗生素和类固醇冲击治疗,急性肺损伤仍进展。他在第33天死于呼吸衰竭。血清检测显示乙肝表面抗原和e抗原,CT扫描显示腹水和脾肿大;临床病程可能因肝硬化而恶化。高效液相色谱法显示血清中有聚乙醛(总量80.6微克/毫升)。据最大估计,他摄入了2.7克聚乙醛。尽管日本毒物信息中心报告称,在日本杀螺诱饵中毒在犬类中很常见,但人类中毒罕见。