意大利单采活动全国性调查（2000年）

National survey of apheresis activity in Italy (2000).

作者信息

De Silvestro Giustina, Marson Piero, Russo Gaspare Elios, Vicarioto Maria, Donadel Carla

机构信息

Apheresis Unit, Blood Transfusion Service, University Hospital of Padova, Italy.

出版信息

Transfus Apher Sci. 2004 Feb;30(1):61-71. doi: 10.1016/j.transci.2003.05.003.

DOI:10.1016/j.transci.2003.05.003

PMID:14746823

Abstract

Data collection on apheresis in Italy throughout 2000, including techniques, machines, clinical indications and adverse effects, has been performed by means of a standardized questionnaire. These data provided from 102 Apheresis Units from 19 Italian regions, albeit rough, are sufficiently informative. In 2000 a total number of 164,943 apheresis procedures has been carried out, with a clear-cut prevalence of productive apheresis (90.8%), that has been performed by all Apheresis Units. Lombardy, Venetia and Liguria have been the most active regions for therapeutic apheresis (54.0% of the total activity). Adverse events, predominantly mild ones (i.e., paresthesia due to citrate-induced hypocalcemia) have occurred in 0.59% of productive and in 6.75% of therapeutic apheresis sessions, particularly in the course of peripheral blood stem cell collection (13.0%).

摘要

2000年全年，意大利通过标准化问卷对单采术进行了数据收集，内容包括技术、机器、临床适应症和不良反应。这些来自意大利19个地区102个单采术单位的数据虽然粗略，但信息足够丰富。2000年共进行了164,943例单采术，其中治疗性单采术占明显优势（90.8%），所有单采术单位均开展了治疗性单采术。伦巴第、威尼托和利古里亚是治疗性单采术最活跃的地区（占总活动量的54.0%）。不良事件主要为轻度事件（即枸橼酸盐诱导的低钙血症导致的感觉异常），在治疗性单采术中发生率为6.75%，在治疗性单采术中发生率为0.59%，尤其是在外周血干细胞采集过程中发生率为13.0%。