Rankins Debbie, Bradshaw John, Moss Simon, Georgiou-Karistianis Nellie
School of Humanities and Social Science, Northern Territory University, 0909, Northern Territory, Australia.
J Int Neuropsychol Soc. 2004 Jan;10(1):54-9. doi: 10.1017/S1355617704101070.
Obsessive-compulsive disorder (OCD) is characterized by repetitive obsessions and/or compulsions that interfere with daily functioning. Neuropsychological studies have suggested that such perseverative behaviors may be due to underlying attentional deficits. Inhibition of return (IOR) is an adaptive mechanism that is thought to assist visual search by biasing attention after a critical, short interval to novel, previously unattended areas. Therefore, this study aimed to examine whether deficient IOR mechanisms could underlie some of the attentional, and perhaps behavioral, problems, reported in OCD patients. Using a computerized IOR paradigm, participants were required to respond to a target that appeared at either the same or different location to a precue that was presented either 100 ms or 700 ms earlier. Results indicate that patients had a reduced IOR for targets presented in the left visual field, suggesting lateralized anomalies in shifting attention. Results are consistent with lateralization anomalies previously reported in OCD.
强迫症（OCD）的特征是反复出现的强迫观念和/或强迫行为，这些会干扰日常功能。神经心理学研究表明，这种持续性行为可能是由于潜在的注意力缺陷所致。返回抑制（IOR）是一种适应性机制，被认为通过在一段关键的短时间间隔后将注意力偏向新的、先前未被关注的区域来辅助视觉搜索。因此，本研究旨在检验IOR机制缺陷是否可能是强迫症患者报告的一些注意力问题以及可能的行为问题的潜在原因。使用计算机化的IOR范式，要求参与者对出现在与100毫秒或700毫秒前呈现的预提示相同或不同位置的目标做出反应。结果表明，患者对左视野中呈现的目标的IOR降低，这表明在转移注意力方面存在偏侧化异常。结果与先前在强迫症中报道的偏侧化异常一致。
