Wu YingXing, Grunkemeier Gary L, Handy John R
Providence Health System, Portland, OR, USA.
J Thorac Cardiovasc Surg. 2004 Jan;127(1):174-8. doi: 10.1016/j.jtcvs.2003.08.018.
This study was undertaken to test whether risk models developed from on-pump coronary artery bypass grafting are valid for assessing the risk for off-pump coronary artery bypass grafting.
From January 1997 through June 2002, a total of 12,845 patients underwent isolated coronary artery bypass grafting procedures in Providence Health System hospitals. Of these, 1782 operations (14%) were performed without cardiopulmonary bypass. An operative mortality risk model was derived from on-pump data with logistic regression. This model and two other external risk models developed from on-pump data were then applied to patients undergoing off-pump coronary artery bypass grafting to test the model adequacy.
Good model discrimination and calibration were obtained from all three models.
Operative mortality risk models developed from on-pump coronary artery bypass grafting can be used to assess the risk for off-pump coronary artery bypass grafting.
本研究旨在测试从体外循环冠状动脉搭桥术得出的风险模型是否适用于评估非体外循环冠状动脉搭桥术的风险。
从1997年1月至2002年6月，普罗维登斯医疗系统医院共有12845例患者接受了单纯冠状动脉搭桥手术。其中，1782例手术（14%）在没有体外循环的情况下进行。通过逻辑回归从体外循环数据中得出手术死亡风险模型。然后将该模型以及另外两个从体外循环数据得出的外部风险模型应用于接受非体外循环冠状动脉搭桥术的患者，以测试模型的适用性。
所有三个模型均获得了良好的模型区分度和校准度。
从体外循环冠状动脉搭桥术得出的手术死亡风险模型可用于评估非体外循环冠状动脉搭桥术的风险。
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