肝硬化患者钆增强磁共振成像后出现假性低钙血症。

Pseudohypocalcemia after magnetic resonance imaging with gadolinium in patients with cirrhosis.

作者信息

Kefalas Costas H, Murray Natalie G B, Aguanno James J, Dockery William D, Weinstein Jeffrey S, Anderson Katherine, Klintmalm Goran B

机构信息

Division of Gastroenterology, Deparment of Internal Medicine, Baylor University Medical Center, Dallas, TX 75246, USA.

出版信息

Liver Transpl. 2004 Jan;10(1):136-40. doi: 10.1002/lt.20008.

DOI:10.1002/lt.20008

PMID:14755791

Abstract

Hypocalcemia in patients with cirrhosis may be due to a number of causes. We noted a relationship between injection with gadodiamide, a particular gadolinium chelate, during magnetic resonance imaging of the liver and the development of a falsely low serum total calcium level in a patient with cirrhosis. A cross-reference and retrospective chart review identified 10 additional patients in whom this phenomenon was noted. We describe the temporal relationship and clinical characteristics of these patients. Pseudohypocalcemia following magnetic resonance imaging with gadodiamide contrast should be considered in the differential diagnosis of hypocalcemia in patients with cirrhosis.

摘要

肝硬化患者的低钙血症可能由多种原因引起。我们注意到，在一名肝硬化患者进行肝脏磁共振成像期间注射钆双胺（一种特定的钆螯合物）与血清总钙水平假性降低的发生之间存在关联。通过交叉引用和回顾性病历审查，又发现了10例出现这种现象的患者。我们描述了这些患者的时间关系和临床特征。在肝硬化患者低钙血症的鉴别诊断中，应考虑钆双胺对比剂磁共振成像后出现的假性低钙血症。