Drug V L, Popa Ingrid, Cijevschi Cristina, Miron L, Mitrică Dana, Stanciu C
Institutul de Gastroenterologie şi Hepatologie, Facultatea de Medicină, Universitatea de Medicina si Farmacie Gr.T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2003 Apr-Jun;107(2):298-305.
Patients with unknown primary site cancer represents 5% to 10% of all neoplasia patients. Liver is a favourite site for gastrointestinal tumors, but not only. The adenocarcinomas represents 60% of patients from this group. A detailed physical examination, extensive laboratory and imaging procedures are necessary to locate the primary tumor. However, liver biopsy could be essential for histological diagnosis and important to identify the tumors who may benefit from specific and effective therapy (breast cancer, prostate cancer, ovarian cancer and small-cell carcinoma of the lung). Systemic chemotherapy represents the most frequently treatment, but only patients with good performance status and without co-morbidities may benefit. "Best supporting care" may be the optimal treatment for most patients, majority with poor performance status at the time of diagnosis.
原发部位不明的癌症患者占所有肿瘤患者的5%至10%。肝脏是胃肠道肿瘤的常见转移部位，但不仅如此。腺癌占该组患者的60%。需要进行详细的体格检查、广泛的实验室检查和影像学检查来定位原发肿瘤。然而，肝活检对于组织学诊断可能至关重要，对于确定可能从特定有效治疗（乳腺癌、前列腺癌、卵巢癌和肺小细胞癌）中获益的肿瘤也很重要。全身化疗是最常用的治疗方法，但只有身体状况良好且无合并症的患者可能从中获益。“最佳支持治疗”可能是大多数患者的最佳治疗方法，大多数患者在诊断时身体状况较差。
Zotero 插件