A型和B型肉毒杆菌毒素的临床应用史。

History of the clinical use of botulinum toxin A and B.

作者信息

Carruthers Alastair

机构信息

Division of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Clin Dermatol. 2003 Nov-Dec;21(6):469-72. doi: 10.1016/j.clindermatol.2003.11.003.

DOI:10.1016/j.clindermatol.2003.11.003

PMID:14759577

Abstract

The history of the cosmetic use of botulinum toxin (BTX) must begin with the clinical use of BTX in humans. This came out of Alan Scott's work, which was initially an attempt to find a nonsurgical treatment for some forms of strabismus. Alan Scott put together the idea of Ed Maumenee to use BTX to affect extraocular muscles, Art Jampolsky's electromyographic control delivery system, and Ed Schantz' work on the purification of BTX.

摘要

肉毒杆菌毒素（BTX）在美容领域的应用历史必须从其在人类身上的临床应用说起。这源于艾伦·斯科特的研究工作，其最初旨在寻找一种非手术方法来治疗某些形式的斜视。艾伦·斯科特整合了埃德·莫梅尼使用BTX影响眼外肌的想法、阿特·詹波尔斯基的肌电图控制给药系统，以及埃德·尚茨在BTX纯化方面的工作。