Schwarz Frank, Sculean Anton, Georg Thomas, Becker Jürgen
Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany.
J Clin Periodontol. 2003 Nov;30(11):975-81. doi: 10.1034/j.1600-051x.2003.00412.x.
The aim of the present study was to compare the combination therapy of deep intrabony periodontal defects using an Er:YAG laser (ERL) and enamel matrix protein derivative (EMD) to scaling and root planing+ ethylenediaminetetraacetic acid (EDTA)+EMD.
Twenty-two patients with chronic periodontitis, each of whom displayed 1 intrabony defect, were randomly treated with access flap surgery and defect debridement with an Er:YAG (160 mJ/pulse, 10 Hz) plus EMD (test) or with access flap surgery followed by scaling and root planing (SRP) with hand instruments plus EDTA and EMD (control). The following clinical parameters were recorded at baseline and at 6 months: plaque index, gingival index, bleeding on probing (BOP), probing depth (PD), gingival recession, and clinical attachment level (CAL). No differences in any of the investigated parameters were observed at baseline between the two groups.
Healing was uneventful in all patients. At 6 months after therapy, the sites treated with ERL and EMD showed a reduction in mean PD from 8.6 +/- 1.2 mm to 4.6 +/- 0.8 mm and a change in mean CAL from 10.7 +/- 1.3 mm to 7.5 +/- 1.4 mm (p < 0.001). In the group treated with SRP+EDTA+EMD, the mean PD was reduced from 8.1 +/- 0.8 mm to 4.0 +/- 0.5 mm and the mean CAL changed from 10.4 +/- 1.1 mm to 7.1 +/- 1.2 mm (p < 0.001). No statistically significant differences in any of the investigated parameters were observed between the test and control group.
Within the limits of the present study, it may be concluded that both therapies led to short-term improvements of the investigated clinical parameters, and the combination of ERL and EMD does not seem to improve the clinical outcome of the therapy additionally compared to SRP+EDTA+EMD.
本研究旨在比较使用铒激光(ERL)和釉基质蛋白衍生物(EMD)联合治疗重度骨内牙周缺损与龈下刮治术+乙二胺四乙酸(EDTA)+EMD治疗的效果。
22例慢性牙周炎患者,每人有1个骨内缺损,随机接受入路翻瓣手术及铒激光(160 mJ/脉冲,10 Hz)联合EMD治疗(试验组),或入路翻瓣手术,随后用手用器械进行龈下刮治术(SRP)联合EDTA及EMD治疗(对照组)。在基线和6个月时记录以下临床参数:菌斑指数、牙龈指数、探诊出血(BOP)、探诊深度(PD)、牙龈退缩和临床附着水平(CAL)。两组在基线时所研究的任何参数均未观察到差异。
所有患者愈合顺利。治疗6个月后,ERL联合EMD治疗的部位平均PD从8.6±1.2 mm降至4.6±0.8 mm,平均CAL从10.7±1.3 mm变为7.5±1.4 mm(p<0.001)。在SRP+EDTA+EMD治疗组,平均PD从8.1±0.8 mm降至4.0±0.5 mm,平均CAL从10.4±1.1 mm变为7.1±1.2 mm(p<0.001)。试验组和对照组在任何研究参数上均未观察到统计学上的显著差异。
在本研究的范围内,可以得出结论,两种治疗方法均使所研究的临床参数得到短期改善,并且与SRP+EDTA+EMD相比,ERL联合EMD似乎并未额外改善治疗的临床效果。