Finnerup N B, Gyldensted C, Fuglsang-Frederiksen A, Bach F W, Jensen T S
Departments of Neurology and Danish Pain Research Centre Neuroradiology Clinical Neurophysiology, Aarhus University Hospital, Aarhus, Denmark.
Acta Neurol Scand. 2004 Mar;109(3):194-9. doi: 10.1034/j.1600-0404.2003.00219.x.
To describe sensations evoked by painful or repetitive stimulation below injury level in patients with a clinically complete (American Spinal Injury Association, ASIA Grade A) spinal cord injury (SCI).
Twenty-four patients (11 with central neuropathic pain and 13 without pain) with a traumatic SCI above the tenth thoracic vertebra were examined using quantitative sensory testing, MR imaging, and somatosensory evoked potentials (SEP).
Painful (pressure, pinch, heat or cold) or repetitive (pinprick) stimuli elicited vague localized sensations in 12 patients (50%). Pain, spasticity, and spasms were equally seen in SCI patients with or without localized sensations. SEP and MRI did not differentiate between these two groups.
The present study suggests retained sensory communication across the injury in complete SCI, i.e. 'sensory discomplete' SCI.
描述临床完全性(美国脊髓损伤协会,ASIA A级)脊髓损伤(SCI)患者损伤平面以下由疼痛或重复性刺激诱发的感觉。
对24例胸十以上创伤性SCI患者(11例有中枢性神经病理性疼痛,13例无疼痛)进行定量感觉测试、磁共振成像和体感诱发电位(SEP)检查。
12例患者(50%)对疼痛性(压力、捏、热或冷)或重复性(针刺)刺激产生模糊的局部感觉。有或无局部感觉的SCI患者中疼痛、痉挛和抽搐的发生率相同。SEP和MRI无法区分这两组患者。
本研究提示在完全性SCI中存在损伤平面以上保留的感觉传导,即“感觉不完全性”SCI。