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[新生儿期健康婴儿体内胆红素的生理水平与行为]

[Physiologic levels of bilirubin and behavior in healty infants during the neonatal period].

作者信息

de Cáceres y Zurita M L, Costas i Moragas C, Botet i Mussons F, Rosales Vidal-Quadras S

机构信息

Departamento de Psicología de la Salud, Facultad de Psicología, Universidad Autónoma de Barcelona.

出版信息

An Esp Pediatr. 1992 Dec;37(6):466-8.

PMID:1482017
Abstract

The purpose of this study was to evaluate behavioral differences in healthy newborns in relationship to bilirubin serum levels within the normal physiological range. Seventy-three healthy full-term newborns of adequate weight for their gestational age had bilirubin levels measured in a blood sample obtained by heel puncture on the third day of life. The Brazelton Neonatal Behavioral Assessment Scale (NBAS, 1984 version) was administered between the 60th and 80th hours of life. Results showed a mean bilirubin value of 123.12 mumol/L (7.2 mg/dL). There was an inverse correlation between serum bilirubin levels and behavior in regards to habituation, orientation, motor maturity and interaction of the NBAS. Although it can not be concluded that physiological bilirubin levels cause significant neurological disturbances, these results suggest that newborns with higher physiological bilirubin levels have some difficulties interacting with their caretakers.

摘要

本研究的目的是评估健康新生儿在正常生理范围内血清胆红素水平与行为差异之间的关系。73名足月健康、体重与其胎龄相符的新生儿在出生第三天通过足跟穿刺采集血样测量胆红素水平。在出生后60至80小时之间进行了布雷泽尔顿新生儿行为评估量表(NBAS,1984年版)测试。结果显示胆红素平均水平为123.12μmol/L(7.2mg/dL)。在NBAS的习惯化、定向、运动成熟度和互动方面,血清胆红素水平与行为之间存在负相关。虽然不能得出生理性胆红素水平会导致明显神经功能障碍的结论,但这些结果表明,生理性胆红素水平较高的新生儿在与照顾者互动方面存在一些困难。

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