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[在无呼吸功能障碍受试者中采用乙炔再呼吸法测量肺血流量]

[Pulmonary blood flow measurement by acetylene rebreathing method in subjects without respiratory function disturbance].

作者信息

Ichinose Y, Torii Y, Yonemaru M, Utsumi K, Minemura K, Kasuga I, Toyama K, Nishi I

机构信息

First Department of Internal Medicine, Tokyo Medical College.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1992 Nov;30(11):1917-22.

PMID:1484429
Abstract

Simultaneous measurement of pulmonary blood flow by the acetylene rebreathing method and cardiac output by the thermodilution method was performed in subjects without respiratory function disturbance during right heart catheterization. After the measurement of cardiac output, the subjects rebreathing a gas mixture containing acetylene and argon from the end tidal level. The inspiratory and expiratory gases were measured by a mass-spectrometer. Results were analyzed by a lung model consisting of two compartments (rebreathing bag compartment and lung compartment), while taking into account the volume reduction due to O2 and CO2 exchange and the fluctuation of end tidal gas concentration until equilibrium between the bag and the lung. The correlation coefficient between these two methods was 0.944, which was statistically significant. The regression line was near the line of identity. The measurement of pulmonary blood flow by the acetylene rebreathing method was applicable in cases without lung function disturbance.

摘要

在右心导管插入术期间,对无呼吸功能障碍的受试者,采用乙炔重呼吸法同步测量肺血流量,并采用热稀释法测量心输出量。在心输出量测量后,受试者从潮气末水平开始重呼吸含有乙炔和氩气的混合气体。吸气和呼气气体用质谱仪测量。结果通过由两个隔室(重呼吸袋隔室和肺隔室)组成的肺模型进行分析,同时考虑到由于氧气和二氧化碳交换导致的体积减少以及在袋和肺之间达到平衡之前潮气末气体浓度的波动。这两种方法之间的相关系数为0.944,具有统计学意义。回归线接近恒等线。乙炔重呼吸法测量肺血流量适用于无肺功能障碍的情况。

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