Mitlehner W, Friedrich M, Dissmann W
1st Department of Internal Medicine (Cardiology and Pneumology), Urban-Krankenhaus, Berlin, FRG.
Respiration. 1992;59(4):221-7. doi: 10.1159/000196062.
In this prospective study, the value of computed tomography (CT) in detecting bullae and bleb formation of the lung in 35 patients with primary spontaneous pneumothorax (PSP) has been determined. The ability of CT in the detection of bullae and bleb formation and fibrotic changes is compared with the chest film in PSP. CT showed pathological lung changes in 31/35 patients. In most cases, few (n < 5) and small blebs (i.e., < 2 cm in diameter) were found. In 16/35 cases, blebs (< 2 cm) and bullae (> 2 cm in diameter) occurred in the extra-apical region. Contralateral pathological changes were found in 23/35. Bullae (> 2 cm) could be detected only in 6/35. In the chest film, bullae and blebs could be detected in 11/35 cases on the ipsilateral (in 2/35 cases not confirmed by CT), in 3/35 on the bilateral and in 4/35 only on the contralateral side. Thus, CT was proved to be of high value in the assessment of bullae and bleb formation in PSP compared with chest film. Negative pressure drainage was instituted as primary therapy. In a follow-up of 9.6 (+/- 5.7 SD) months, only early recurrences were noticed (n = 35). The rate of recurrences was 6/35 patients. The longer follow-up period (mean 31.7 +/- 6.1 months) could be performed for 32 patients; 3 were lost. Additionally, 2 recurrences occurred. No correlation between recurrences and anatomical status (number, size and distribution of blebs/bullae) as assessed by CT was found. Differential treatment protocols on the basis of the initial findings do not appear to be warranted.
在这项前瞻性研究中,已确定计算机断层扫描(CT)在检测35例原发性自发性气胸(PSP)患者肺大疱和肺小疱形成方面的价值。将CT检测肺大疱、肺小疱形成及纤维化改变的能力与PSP患者的胸部X线片进行比较。CT显示31/35例患者有肺部病理改变。在大多数病例中,发现少量(n<5)且小的肺小疱(即直径<2 cm)。16/35例中,肺小疱(<2 cm)和肺大疱(直径>2 cm)出现在肺尖外区域。23/35例发现对侧有病理改变。仅6/35例能检测到肺大疱(>2 cm)。在胸部X线片上,11/35例在同侧可检测到肺大疱和肺小疱(2/35例未得到CT证实),3/35例双侧可检测到,4/35例仅在对侧可检测到。因此,与胸部X线片相比,CT被证明在评估PSP患者肺大疱和肺小疱形成方面具有很高的价值。负压引流作为主要治疗方法。在9.6(±5.7标准差)个月的随访中,仅发现早期复发(n=35)。复发率为6/35例患者。32例患者可进行更长时间的随访(平均31.7±6.1个月);3例失访。另外,又发生了2例复发。未发现复发与CT评估的解剖学状态(肺小疱/肺大疱的数量、大小和分布)之间存在相关性。基于初始检查结果的差异化治疗方案似乎没有必要。