Masutani H, Takahashi H, Sando I
Elizabeth McCullough Knowles Otopathology Laboratory, Department of Otolaryngology, University of Pittsburgh School of Medicine, PA 15213.
Auris Nasus Larynx. 1992;19(3):145-52. doi: 10.1016/s0385-8146(12)80034-4.
To investigate the role of pathology of the stria vascularis in Ménière's disease, the vascularity and the cross-sectional area of the stria vascularis in a midmodiolar section of the cochlea were examined by histological observation and a computer-aided planimetric, respectively, in eight temporal bones from individuals with Ménière's disease and eight age-matched normal temporal bones. The number of vessels in the stria vascularis was significantly smaller in most of the cochlear turns in ears with Ménière's disease than in control ears, and the cross-sectional area of the stria vascularis in the same sections was significantly smaller in all the cochlear turns in ears with Ménière's disease than in controls. Furthermore, vascularity correlated significantly with the cross-sectional area of the stria vascularis in all the temporal bones examined. From these results it appears that poor vascularity of the stria vascularis is closely related to strial atrophy, and that these pathological findings might be important factors in the pathophysiology of Ménière's disease.
为研究血管纹病理在梅尼埃病中的作用，分别通过组织学观察和计算机辅助平面测量法，对8例梅尼埃病患者的颞骨和8例年龄匹配的正常颞骨的耳蜗中轴切片的血管纹血管分布和横截面积进行了检查。梅尼埃病耳大多数耳蜗旋的血管纹血管数量明显少于对照耳，且梅尼埃病耳相同切片中所有耳蜗旋的血管纹横截面积均显著小于对照耳。此外，在所检查的所有颞骨中，血管分布与血管纹横截面积显著相关。从这些结果来看，血管纹血管分布不良与血管纹萎缩密切相关，且这些病理表现可能是梅尼埃病病理生理学中的重要因素。
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