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[体外受精刺激过程中的卵巢过度刺激综合征。圣安托万妇产科辅助生殖中心的经验与文献综述比较]

[Ovarian hyperstimulation syndrome during in vitro fertilization stimulations. Comparison between the experience of the Center for Medically Assisted Procreation of the Saint Antoine maternity department and a review of the literature].

作者信息

Guettier X, Larue L, Chamorand E, Barbier D, Jault T, Liou Y, Marpeau L, Barrat J

机构信息

Service de Gynécologie-Obstétrique, Hôpital Saint-Antoine, Paris.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1992;21(8):887-95.

PMID:1491132
Abstract

The authors present their experience with the severe ovarian hyperstimulation syndrome when they were using stimulation for IVF and ET and they compare it with the literature. Over a period of 23 months. 154 stimulations were carried out using a long protocol associated with a CnRH agonist and hMG. 142 vaginal aspirations were carried out. The clinical pregnancy rate was 19% per aspiration and 21.9% per transfer. Of the 142 patients who were aspirated five had severe ovarian hyperstimulation with a favourable outcome. The authors suggest a physiopathological comparison for ovarian hyperstimulation and the management to be carried out when this complication occurs. They emphasise how potentially serious this complication is and that there has been no physiopathological explanation for its recrudescence since GnRH agonist have started to be used.

摘要

作者介绍了他们在使用刺激方案进行体外受精和胚胎移植时治疗严重卵巢过度刺激综合征的经验,并与文献进行了比较。在23个月的时间里,采用与促性腺激素释放激素激动剂和人绝经期促性腺激素相关的长方案进行了154次刺激。进行了142次经阴道抽吸。每次抽吸的临床妊娠率为19%,每次移植的临床妊娠率为21.9%。在142例接受抽吸的患者中,有5例发生严重卵巢过度刺激,结果良好。作者建议对卵巢过度刺激进行生理病理学比较,并提出发生这种并发症时的处理方法。他们强调这种并发症的潜在严重性,并且自从开始使用促性腺激素释放激素激动剂以来,对于其复发尚无生理病理学解释。

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