Bittner R C, Schörner W, Loddenkemper C, Auffermann W, Schönfeld N, Hieckel H G, Thalhofer S, Dorow P, Krumhaar D, Kaiser D
Strahlen- und Poliklinik, Universitätsklinikum Rudolf Virchow, Berlin.
Pneumologie. 1992 Dec;46(12):612-20.
MR images of 48 patients with histologically confirmed benign and malignant diseases of the pleura were retrospectively compared with CT and bioptically/surgically obtained findings. In 47/48 patients pathological changes of the pleura were visualized by increased signal intensities on T2-weighted and contrast enhanced T1-weighted MR images. This lead to a slightly improved sensitivity compared to CT, where pathological pleura findings were confirmed in 45/48 patients. MRI was able to identify 24/28 confirmed pleural effusions, whereas CT was successful in 26/28 patients. In two cases effusions not identified on CT were visible on T2-weighted MRI. 4 pleural effusions were missed with MRI.. On CT images differentiation of pleural changes vs effusions or adjacent lesions of lung parenchyma was successful in 20/28 and in 17/23 cases, respectively. Contrast enhanced T1-weighted images achieved the highest diagnostic accuracy with 22/28 and 20/23 cases, respectively. Signal intensities on MRI were unsuitable as sole criterion for the differentiation of benign and malignant diseases of the pleura. Contour and pattern of spreading of pleural changes were helpful in differential diagnosis. Nodular changes, thickening of more than 10 mm and mediastinal, circumferential and entire hemithoracic affection of the pleura were suggestive for malignant pleural disease. Infiltration of the diaphragm and the chest wall were most indicative for malignancy; here MRI (2/2 resp. 18/19 cases) was superior to CT (0/2 resp. 14/19 cases). CT was superior in the detection of pleural calcifications and osseous destruction.(ABSTRACT TRUNCATED AT 250 WORDS)
对48例经组织学证实患有胸膜良恶性疾病的患者的磁共振成像(MR)图像进行回顾性分析,并与计算机断层扫描(CT)以及活检/手术获得的结果进行比较。在48例患者中的47例中,胸膜的病理改变在T2加权和对比增强T1加权MR图像上表现为信号强度增加。与CT相比,这使得敏感性略有提高,CT在48例患者中的45例中证实了胸膜的病理发现。MRI能够识别出28例经证实的胸腔积液中的24例,而CT在28例患者中的26例中成功识别。在2例病例中,CT未发现的胸腔积液在T2加权MRI上可见。MRI漏诊了4例胸腔积液。在CT图像上,分别有28例中的20例和23例中的17例成功区分了胸膜改变与胸腔积液或肺实质的相邻病变。对比增强T1加权图像分别在28例中的22例和23例中的20例中达到了最高的诊断准确性。MRI上的信号强度不适宜作为区分胸膜良恶性疾病的唯一标准。胸膜改变的轮廓和扩散模式有助于鉴别诊断。结节状改变、超过10毫米的增厚以及胸膜的纵隔、圆周和全胸受累提示为恶性胸膜疾病。膈肌和胸壁的浸润最提示为恶性;在此方面,MRI(分别为2/2和18/19例)优于CT(分别为0/2和14/19例)。CT在检测胸膜钙化和骨质破坏方面更具优势。(摘要截取自250字)