García-Rodríguez J A, Casal M, Rodríguez F
Servicio de Microbiología, Hospital Universitario de Salamanca, Salamanca, Spain.
Rev Esp Quimioter. 2003 Dec;16(4):421-7.
A study was conducted from 1997 to 2001 on the trends of the antibiotic resistance of Pseudomonas aeruginosa, Escherichia coli and Bacteroides fragilis in a Spanish multicenter study involving 26 hospitals. During the five years of the study the susceptibility by 81,779 strains of P. aeruginosa, 306,689 strains of E. coli and 2866 strains of B. fragilis to at least one antibiotic were studied. When the three microorganisms were considered together, meropenem (3.49%), piperacillin-tazobactam (5.54%) and imipenem (5.27%) were the antibiotics to which they showed the lowest resistance rate.
1997年至2001年,在一项涉及26家医院的西班牙多中心研究中,对铜绿假单胞菌、大肠杆菌和脆弱拟杆菌的抗生素耐药性趋势进行了研究。在研究的五年中,对81779株铜绿假单胞菌、306689株大肠杆菌和2866株脆弱拟杆菌对至少一种抗生素的敏感性进行了研究。当将这三种微生物一起考虑时,美罗培南(3.49%)、哌拉西林-他唑巴坦(5.54%)和亚胺培南(5.27%)是它们耐药率最低的抗生素。