Karlberg Mikael, Annertz Mårten, Magnusson Måns
Department of Otorhinolaryngology-Head and Neck Surgery, Lund University Hospital, Lund, Sweden.
Arch Otolaryngol Head Neck Surg. 2004 Feb;130(2):229-32. doi: 10.1001/archotol.130.2.229.
Sudden idiopathic unilateral loss of vestibular function without other signs or symptoms is called acute vestibular neuritis. It has been suggested that reactivation of human herpes simplex virus 1 could cause vestibular neuritis, Bell palsy, and sudden unilateral hearing loss. Enhancement of the facial nerve on gadolinium-enhanced magnetic resonance imaging (MRI) is a common finding in Bell palsy, but enhancement of the vestibular nerve has never been reported in acute vestibular neuritis. We present 2 consecutive cases of acute vestibular neuritis where high-field-strength MRI (3.0 T) with high-dose (0.3 mmol/kg of body weight) gadolinium-pentetic acid showed isolated enhancement of the vestibular nerve on the affected side only. These findings support the hypothesis of a viral and inflammatory cause of acute vestibular neuritis and might have implications for its treatment.
突发特发性单侧前庭功能丧失且无其他体征或症状被称为急性前庭神经炎。有人提出,人类单纯疱疹病毒1的重新激活可能导致前庭神经炎、贝尔面瘫和突发性单侧听力损失。钆增强磁共振成像(MRI)上面神经强化是贝尔面瘫的常见表现,但急性前庭神经炎中前庭神经强化从未有过报道。我们报告了2例连续的急性前庭神经炎病例,高场强MRI(3.0T)联合高剂量(0.3mmol/kg体重)钆喷替酸显示仅患侧前庭神经出现孤立性强化。这些发现支持急性前庭神经炎由病毒和炎症引起的假说,可能对其治疗具有启示意义。