Markel H
Institute of the History of Medicine, Johns Hopkins University, Baltimore, Maryland 21205.
Am J Med. 1992 Aug;93(2):209-15. doi: 10.1016/0002-9343(92)90052-d.
As the field of human genetics successfully continues to unravel the secrets of an individual's genetic makeup, the social processes of stigmatization and ostracism of those with "undesirable" traits have the potential to increase. An historical example that may shed light on the problems of applying genetic technology to disease prevention is the institution of quarantine. This essay discusses the concept of "quarantine mentality" and the desire for healthy society to separate itself from those labeled "ill" or abnormal, and addresses two episodes in American history when genetics was applied to the formulation of social policy toward the "diseased": the eugenics movement of the early 20th century and the early attempts of genetic screening programs for sickle cell anemia during the 1970s.
随着人类遗传学领域持续成功地揭开个体基因构成的秘密,对具有“不良”特征者进行污名化和排斥的社会进程有可能加剧。检疫制度是一个历史实例,或许能为将基因技术应用于疾病预防所产生的问题提供启示。本文探讨了“检疫心态”的概念,以及健康社会将自身与那些被贴上“患病”或异常标签者隔离开来的愿望,并论述了美国历史上基因学被用于制定针对“患病者”的社会政策的两个事件:20世纪初的优生学运动,以及20世纪70年代针对镰状细胞贫血的基因筛查项目的早期尝试。