Trivedi M H, Rush A J, Ibrahim H M, Carmody T J, Biggs M M, Suppes T, Crismon M L, Shores-Wilson K, Toprac M G, Dennehy E B, Witte B, Kashner T M
Department of Psychiatry and Academic Computing Services, University of Texas, Southwestern Medical Center at Dallas 75235, USA.
Psychol Med. 2004 Jan;34(1):73-82. doi: 10.1017/s0033291703001107.
The present study provides additional data on the psychometric properties of the 30-item Inventory of Depressive Symptomatology (IDS) and of the recently developed Quick Inventory of Depressive Symptomatology (QIDS), a brief 16-item symptom severity rating scale that was derived from the longer form. Both the IDS and QIDS are available in matched clinician-rated (IDS-C30; QIDS-C16) and self-report (IDS-SR30; QIDS-SR16) formats.
The patient samples included 544 out-patients with major depressive disorder (MDD) and 402 out-patients with bipolar disorder (BD) drawn from 19 regionally and ethnicically diverse clinics as part of the Texas Medication Algorithm Project (TMAP). Psychometric analyses including sensitivity to change with treatment were conducted.
Internal consistencies (Cronbach's alpha) ranged from 0.81 to 0.94 for all four scales (QIDS-C16, QIDS-SR16, IDS-C30 and IDS-SR30) in both MDD and BD patients. Sad mood, involvement, energy, concentration and self-outlook had the highest item-total correlations among patients with MDD and BD across all four scales. QIDS-SR16 and IDS-SR30 total scores were highly correlated among patients with MDD at exit (c = 0.83). QIDS-C16 and IDS-C30 total scores were also highly correlated among patients with MDD (c = 0.82) and patients with BD (c = 0.81). The IDS-SR30, IDS-C30, QIDS-SR16, and QIDS-C16 were equivalently sensitive to symptom change, indicating high concurrent validity for all four scales. High concurrent validity was also documented based on the SF-12 Mental Health Summary score for the population divided in quintiles based on their IDS or QIDS score.
The QIDS-SR16 and QIDS-C16, as well as the longer 30-item versions, have highly acceptable psychometric properties and are treatment sensitive measures of symptom severity in depression.
本研究提供了关于30项抑郁症状量表(IDS)以及最近开发的快速抑郁症状量表(QIDS,一种由较长版本衍生而来的简短的16项症状严重程度评定量表)心理测量特性的更多数据。IDS和QIDS都有相应的临床医生评定版本(IDS - C30;QIDS - C16)和自我报告版本(IDS - SR30;QIDS - SR16)。
患者样本包括从19个地域和种族多样的诊所选取的544例重度抑郁症(MDD)门诊患者和402例双相情感障碍(BD)门诊患者,作为德克萨斯药物治疗算法项目(TMAP)的一部分。进行了包括对治疗变化敏感性的心理测量分析。
在MDD和BD患者中,所有四个量表(QIDS - C16、QIDS - SR16、IDS - C30和IDS - SR30)的内部一致性(克朗巴哈系数)范围为0.81至0.94。在MDD和BD患者的所有四个量表中,悲伤情绪、参与度、精力、注意力和自我认知的项目总分相关性最高。在MDD患者治疗结束时,QIDS - SR16和IDS - SR30总分高度相关(c = 0.83)。在MDD患者(c = 0.82)和BD患者(c = 0.81)中,QIDS - C16和IDS - C30总分也高度相关。IDS - SR30、IDS - C30、QIDS - SR16和QIDS - C16对症状变化的敏感性相当,表明所有四个量表具有较高的同时效度。基于根据IDS或QIDS评分分为五等份的人群的SF - 12心理健康总结评分,也证明了较高的同时效度。
QIDS - SR16和QIDS - C16以及较长的30项版本具有高度可接受的心理测量特性,是抑郁症症状严重程度的治疗敏感性测量指标。