Grow Matthew P, Singh Amrik, Fleming Neal W, Young Nilas, Watnik Mitchell
Department of Anesthesiology, University of California Davis, Sacramento, CA 95817, USA.
J Cardiothorac Vasc Anesth. 2004 Feb;18(1):43-6. doi: 10.1053/j.jvca.2003.10.009.
To evaluate and compare monitors of cardiac output during repositioning and stabilization of the heart for off-pump coronary artery bypass (OPCAB) surgery.
Prospective, observational, clinical study.
University teaching hospital.
Consecutive patients scheduled to undergo elective OPCAB (n = 19).
Monitoring, induction, and anesthesia followed a routine protocol for coronary artery bypass patients. This included the use of transesophageal echocardiography (TEE) and pulmonary artery catheter placement.
After positioning and stabilization for OPCAB surgery, the changes in descending aortic flow velocity (VTI) times heart rate (HR) and the mixed venous oxygen saturation (SvO(2)) could be used to predict the changes in thermodilution cardiac output (TDCO) using the following model: deltaTDCO((calc))=-13.15+0.35(deltaVTI*HR)+0.61(deltaSvO(2)) where Delta indicates the percentage change from baseline values. The changes in mean arterial pressure, mean pulmonary artery pressure, and continuous cardiac output did not correlate with the changes in TDCO.
The use of the VTIHR, as determined by TEE, in addition to the SvO(2) can strengthen clinical decision making during repositioning and stabilization of the heart during OPCAB. Changes in the VTIHR and SvO(2) can be used as surrogate markers for changes in CO during OPCAB surgery.
评估并比较在非体外循环冠状动脉搭桥术(OPCAB)心脏重新定位和稳定过程中的心输出量监测器。
前瞻性、观察性临床研究。
大学教学医院。
连续安排接受择期OPCAB手术的患者(n = 19)。
按照冠状动脉搭桥患者的常规方案进行监测、诱导和麻醉。这包括使用经食管超声心动图(TEE)和放置肺动脉导管。
在进行OPCAB手术的心脏定位和稳定后,降主动脉流速时间积分(VTI)乘以心率(HR)以及混合静脉血氧饱和度(SvO₂)的变化可用于通过以下模型预测热稀释心输出量(TDCO)的变化:ΔTDCO(计算值)=-13.15 + 0.35(ΔVTI×HR)+ 0.61(ΔSvO₂),其中Δ表示相对于基线值的百分比变化。平均动脉压、平均肺动脉压和连续心输出量的变化与TDCO的变化无关。
除SvO₂外,使用TEE测定的VTI×HR可加强OPCAB手术中心脏重新定位和稳定过程中的临床决策。VTI×HR和SvO₂的变化可作为OPCAB手术中CO变化的替代指标。