Lewański Robert, Chrzanowski Witold
Klinika Nefrologii z Pododdziałem Dializ Instytutu Medycyny Wewnetrznej UM w Łodzi.
Pol Merkur Lekarski. 2003 Oct;15(88):391-3.
The aim of the presented study was to assess autonomic nervous system (ANS) among hemodialysed patients. Twenty-seven pts. were included to the study (15 M, 12 F) and as a control group 22 (12 M, 10 F) healthy persons were taken. To asses cardiovascular part of ANS we used Ewing battery, time and spectral analysis of heart rate variability (HRV) and spectral analysis of blood pressure variability (BPV). QT interval was analyzed from standard 12-lead ECG. The hemodialysed patients showed certain signs of autonomic dysregulation. Forty two percent of pts had abnormalities in Ewing tests most prevalent in parasympathetic part of ANS. Spectral HRV parameters were pathological in 44.4% patients. The low frequency component of BPV was significantly lower in HD patients without changes in the high frequency component. QT interval dispersion and corrected by heart rate QT interval dispersion were significantly higher in hemodialysed patients than in the control group.
本研究的目的是评估血液透析患者的自主神经系统(ANS)。27例患者(15例男性,12例女性)纳入研究,选取22例(12例男性,10例女性)健康人作为对照组。为评估自主神经系统的心血管部分,我们采用了尤因测试、心率变异性(HRV)的时域和频域分析以及血压变异性(BPV)的频域分析。从标准12导联心电图分析QT间期。血液透析患者表现出一定的自主神经调节异常迹象。42%的患者尤因测试异常,最常见于自主神经系统的副交感部分。44.4%的患者频谱HRV参数呈病理性。血液透析患者的BPV低频成分显著降低,高频成分无变化。血液透析患者的QT间期离散度及心率校正后的QT间期离散度显著高于对照组。