Adsuar Natalie, Blanchette Howard, Kilchevsky Eitan
Department of Obstetrics and Gynecology, Danbury Hospital, 24 Hospital Avenue, Danbury, CT 06810, USA.
J Reprod Med. 2004 Jan;49(1):52-4.
Mycobacterium tuberculosis is the most common cause of tuberculosis in the world. Since the mid-1980s the United States has seen an increase in the incidence of tuberculosis, attributed largely to an increase in patients infected with HIV and to the immigration of infected individuals from endemic areas. The disease affects mainly the lungs, but about one-third of patients also have involvement of other sites. The incidence of peritoneal tuberculosis is low in developed countries and is the sixth most common extrapulmonary site. Laparoscopic biopsy provides a rapid and definitive diagnosis. When promptly diagnosed, tuberculosis is one of the few diffuse peritoneal processes for which there is effective therapy with an excellent prognosis.
A 20-year-old woman with a diffuse peritoneal process and elevated CA-125, suspected to be secondary to ovarian cancer, as diagnosed as having tuberculosis peritonitis. Diagnostic laparoscopy was invaluable in establishing the diagnosis.
Use of CA-125 for diagnosis of ovarian cancer may lead to misdiagnosis and unnecessary, invasive procedures. Suspecting and establishing a diagnosis by laparoscopic biopsy may prevent unnecessary laparotomy.
结核分枝杆菌是全球结核病最常见的病因。自20世纪80年代中期以来,美国结核病发病率有所上升,这主要归因于感染艾滋病毒患者的增加以及来自疫区的感染者的移民。该疾病主要影响肺部,但约三分之一的患者其他部位也会受累。在发达国家,结核性腹膜炎的发病率较低,是肺外结核第六常见的部位。腹腔镜活检可提供快速明确的诊断。一旦及时诊断,结核病是少数几种有有效治疗方法且预后良好的弥漫性腹膜疾病之一。
一名20岁女性,有弥漫性腹膜病变且CA-125升高,怀疑继发于卵巢癌,最终诊断为结核性腹膜炎。诊断性腹腔镜检查对确诊非常重要。
使用CA-125诊断卵巢癌可能导致误诊以及不必要的侵入性检查。通过腹腔镜活检进行怀疑和确诊可避免不必要的剖腹手术。